3-methyl-but-2-enoic acid 7(9)H-purin-6-ylamide | 21589-34-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 英文名称: 3-methyl-but-2-enoic acid 7(9)H-purin-6-ylamide
• 英文别名: 6-N-<3-Methyl-buten-2-oyl>-adenin；3-methyl-N-(7H-purin-6-yl)but-2-enamide
• CAS: 21589-34-4
• 化学式: C₁₀H₁₁N₅O
• 分子量: 217.23
• InChiKey: XMWLDUPONOYDOB-UHFFFAOYSA-N

物化性质

• 密度：
  1.39±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  83.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2933990090

反应信息

• 作为产物：
  描述：

  3-甲基丁-2-烯酰胺 、 6-氯嘌呤 在 三乙胺 作用下， 以 乙醇 为溶剂， 反应 5.0h， 以96.8%的产率得到3-methyl-but-2-enoic acid 7(9)H-purin-6-ylamide
  参考文献：
  名称：

  腺嘌呤及其衍生物的合成方法

  摘要：

  本发明公开了一种腺嘌呤及其衍生物的合成方法，它是先由丙二酸二乙酯与二甲基二氧杂环丙烷经氧化反应得到2‑羟基丙二酸二乙酯；然后与氨水经氨解反应得到2‑羟基丙二酰胺；接着与原甲酸三甲酯经环合反应得到5‑羟基嘧啶‑4,6‑（1H,5H）‑二酮；再与光气经氯化反应得到4,5,6‑三氯嘧啶；再与甲脒盐酸盐经环合反应得到4‑氯‑1H‑吡唑[3,4‑d]嘧啶；最后与氨水或者胺类化合物在三乙胺的存在下经氨化反应得到腺嘌呤或其衍生物。本发明的合成方法原料价廉易得，反应条件温和，反应过程安全，对生产设备要求低，尤其是对环境污染较小，收率较高，从而适合工业化大生产。

  公开号：

  CN106883233B

文献信息

• CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：NAGURA MASATO

  公开号：US20110076423A1

  公开（公告）日：2011-03-31

  A cellulose acylate film comprising a cellulose acylate resin satisfying the formulae (i)-(iii) and a compound capable of forming a hydrogen bond satisfying conditions (A)-(C): (A) the compound has both a hydrogen bond donor moiety and a hydrogen bond acceptor moiety in the molecule, (B) the value obtained by dividing the molecular weight of the compound by the total of the number of the hydrogen bond donor moiety and the number of the hydrogen bond acceptor moiety is from 30 to 65, (C) the number of aromatic ring structures is from 1 to 3, 0.5≦ A+B ≦2.7,  (i) 0.0≦A≦2.5, and  (ii) 0.1≦B≦2.0,  (iii) wherein A means the degree of substitution with an acetyl group, and B means a total of the degree of substitution with a propionyl group and the degree of substitution with a butyryl group.
• Optical performance humidity dependency improving agent for cellulose acylate film
  申请人：Nagura Masato

  公开号：US20110262661A1

  公开（公告）日：2011-10-27

  An optical performance humidity dependency improving agent for cellulose acylate film, which contains a compound having a nucleic acid base skeleton, is capable of preventing the fluctuation of Re and Rth of the film against the humidity change in usage environments.
• Optical film, retardation film, polarizing plate, and liquid crystal display device
  申请人：Sasada Yasuyuki

  公开号：US20120018685A1

  公开（公告）日：2012-01-26

  An optical film contains a cellulose ester and more than 30% by mass, relative to the cellulose ester, of a condensation product of at least one polyhydric alcohol having an average of 2.01 or more carbon atoms and at least one polybasic acid having an average of 4.10 or more carbon atoms, and at least one of the at least one polyhydric alcohol contains at least three carbon atoms bonded together without being interrupted by any other atom.
• Cellulose Acylate Film, Retardation Film, Polarizer and Liquid Crystal Display Device
  申请人：Nagura Masato

  公开号：US20120204757A1

  公开（公告）日：2012-08-16

  A cellulose acylate film comprising a cellulose acylate resin satisfying the formulae (i)-(iii) and a compound capable of forming a hydrogen bond satisfying conditions (A)-(C): (A) the compound has both a hydrogen bond donor moiety and a hydrogen bond acceptor moiety in the molecule, (B) the value obtained by dividing the molecular weight of the compound by the total of the number of the hydrogen bond donor moiety and the number of the hydrogen bond acceptor moiety is from 30 to 65, (C) the number of aromatic ring structures is from 1 to 3, 0.5≦ A+B ≦2.7,  (i) 0.0≦ A ≦2.5, and  (ii) 0.1≦ B ≦2.0,  (iii) wherein A means the degree of substitution with an acetyl group, and B means a total of the degree of substitution with a propionyl group and the degree of substitution with a butyryl group.
• OPTICAL FILM, PHASE DIFFERENCE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：SASADA Yasuyuki

  公开号：US20120231217A1

  公开（公告）日：2012-09-13

  An optical film, including: an additive; a wax component; and a cellulose ester, wherein the optical film satisfies the following equations (1) and (2): Equation (1): |ΔC/Ct|≧0.1×(Ct/d−0.3) and Equation (2): Ct/d≧0.375; wherein Ct represents a total content of the additive whose unit is % by mass, d represents a film thickness whose unit is μm, and ΔC is represented by Ct−Cs; wherein Cs represents a surface content of the additive in at least one side of the optical film.