1,4,5,8-tetra(amino)naphthalene | 2187-88-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1,4,5,8-tetra(amino)naphthalene
• 英文别名: 1,4,5,8-tetra-aminonaphthalene；naphthalene-1,4,5,8-tetraamine；1,4,5,8-tetraaminonaphthalene；1,4,5,8-Naphthalenetetramine；naphthalene-1,4,5,8-tetramine
• CAS: 2187-88-4
• 化学式: C₁₀H₁₂N₄
• 分子量: 188.232
• InChiKey: LJYJFKXQKHSSEB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  104
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,4,5,8-tetra(amino)naphthalene 在 氢溴酸 作用下， 以 N-甲基吡咯烷酮 、 5,5-dimethyl-1,3-cyclohexadiene 、 乙腈 为溶剂， 反应 20.0h， 生成
  参考文献：
  名称：

  一种共轭呸啶缓蚀剂及其制备方法

  摘要：

  本发明公开了一种共轭呸啶缓蚀剂及其制备方法，包括：1,4,5,8‑四氨基萘与取代苯甲酸进行酰化、环化反应，制备得到得到二烷基苯基呸啶；2)二烷基苯基呸啶与氢溴酸进行季铵化反应制备共轭呸啶缓蚀剂；本发明提供的共轭呸啶缓蚀剂分子的共轭程度高，能形成大π键以平面构型吸附于金属表面上，附着力强，使缓蚀率大为提高，可作为铜、铁缓蚀剂，具有良好的缓蚀效果。

  公开号：

  CN112876487B
• 作为产物：
  描述：

  1,4,5,8-tetranitronaphthalene 在 tin(ll) chloride 作用下， 以 盐酸 、 乙醇 为溶剂， 反应 2.5h， 以82%的产率得到1,4,5,8-tetra(amino)naphthalene
  参考文献：
  名称：

  萘二甲胺：XXXIV。1,4,5,8-四（二甲基氨基）萘：合成的替代方法

  摘要：

  New methods were proposed for synthesizing 1,4,5,8-tetrakis(dimethylamino)naphthalene with an overall yield of 4 to 12% to replace the known procedure ensuring an overall yield of 2%. Catalytic hydrogenation was shown to be inapplicable for preparation of polyaminonaphthalenes from nitro compounds having 3 or 4 nitro gruops in the alpha-positions. Nucleophilic amination of 1,5-dinitronaphthalene in the system NH2OH/NaOH/MeOH yields 1-amino-4-nitronaphthalene. The nitration of 1,5-bis(p-tolylsulfonylamino)naphthalene leads to formation of 2,6-dinitro rather than 4,8-dinitro derivative, as it was believed formerly. This was confirmed by transformation of the latter into 1,2,5,6-tetrakis(dimethylamino)naphthalene. 3-Nitro, 2,6-dinitro, 2,6-diamino, and 2,4,6,8-tetranitro derivatives of 1,5-bis(dimethylamino)naphthalene, nitro and amino derivatives of 1,4,5-tris(dimethylamino)naphthalene, and 4,5-diamino-1,8-bis(methylamino)naphthalene were synthesized. By treatment with perchloric acid 1,4,5,8-tetrakis(dimethylamino)naphthalene was oxidized to 2,3-dihydroperimidinium salt.

  DOI：

  10.1023/a:1019615206870

文献信息

• Suppository and composition comprising at least one polyethylene glycol
  申请人：Anestic ApS

  公开号：US20020048601A1

  公开（公告）日：2002-04-25

  There is provided a suppository comprising at least one biocompatible polymer, wherein the biocompatible polymer is essentially non-biodegradable, and wherein the suppository essentially does not swell when contacted with an aqueous fluid. The suppository may further comprise a plurality of open cells at least partly separated from one another by an interpenetrating matrix comprising at least one biocompatible polymer in branched or crosslinked form. The plurality of interlinked, open cells are capable of containing an aqueous fluid, and the permeability of the suppository ensures that entry of body fluids into the open cells under practical circumstances occurs essentially without dehydration of mucousal membrane tissue contacting the suppository. The suppository furthermore preferably comprises a controlled release formulation.

  提供了一种含有至少一种生物相容性聚合物的栓剂，其中该生物相容性聚合物基本上不可生物降解，且当与水性液体接触时，该栓剂基本上不膨胀。该栓剂还可以进一步包括多个开放单元，这些单元至少部分地由相互穿插的基质分隔开，该基质包含至少一种分支或交联形式的生物相容性聚合物。这些互相连接的开放单元能够包含水性液体，而栓剂的渗透性确保体液进入开放单元时，在实际情况下基本上不会导致接触栓剂的粘膜组织脱水。此外，该栓剂最好包含控制释放配方。
• NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR
  申请人：OSAKA UNIVERSITY

  公开号：US20190337966A1

  公开（公告）日：2019-11-07

  In order to provide a naphthobischalcogenadiazole derivative that can be used as an intermediate for producing a naphthobischalcogenadiazole compound into which a fluorine atom has been introduced, the naphthobischalcogenadiazole derivative in accordance with an aspect of the present invention is represented by a formula (I): where each of A 1 and A 2 is independently an oxygen atom, a sulfur atom, a selenium atom, or a tellurium atom; and each of X 1 and X 2 is independently a hydrogen atom, a halogen atom, a boronic acid group, a boronic acid ester group, a boronic acid diaminonaphthalene amide group, an N-methyliminodiacetic acid boronate group, a trifluoroborate salt group, or a triolborate salt group.

  为了提供一种可用作生产引入氟原子的萘基双硫/硒/碲-二唑化合物的中间体的萘基双硫/硒/碲-二唑衍生物，本发明的一个方面提供的萘基双硫/硒/碲-二唑衍生物由式(I)表示：其中，A1和A2分别独立地为氧原子、硫原子、硒原子或碲原子；X1和X2分别独立地为氢原子、卤素原子、硼酸基、硼酸酯基、硼酸二氨基萘酰胺基、N-甲基亚乙二酸硼酸酯基、三氟硼酸盐基或三羟基硼酸盐基。
• Dual role of polyphosphoric acid-activated nitroalkanes in oxidative peri-annulations: efficient synthesis of 1,3,6,8-tetraazapyrenes
  作者：Alexander V. Aksenov、Dmitrii S. Ovcharov、Nicolai A. Aksenov、Dmitrii A. Aksenov、Oleg N. Nadein、Michael Rubin

  DOI：10.1039/c7ra04751g

  日期：——

  Electrophilically activated nitroalkanes play a dual role in the novel reaction with diaminoperimidines, promoting their oxidative peri-annulation to access tetraazapyrenes.

  电愿活化的硝基烷在与二氨基苯并咪唑反应中发挥双重作用，促进其氧化的peri-环化，以制备四氮杂苝。
• ORGANIC ELECTROLUMINESCENT DEVICE
  申请人：Merck Patent GmbH

  公开号：US20170077418A1

  公开（公告）日：2017-03-16

  The present invention relates to organic electroluminescent devices, the emitting layer thereof containing a blend of a luminescent material having a narrow singlet-triplet gap and a fluorescent emission material having high steric shielding.

  本发明涉及有机电致发光器件，其中发光层包含具有狭窄单重-三重能隙的发光材料和具有高立体屏蔽的荧光发射材料的混合物。
• A Fluorescent Blue Phosphazene Dye: Synthesis, Structure and Optical Properties of 1,6-Bis(Dimethylamino)-2,5,7,10-Tetraazo-1,6λ5-Diphosphapyrene
  作者：Anna Lebkücher、Arina Rybina、Dirk-Peter Herten、Olaf Hübner、Hubert Wadepohl、Elisabeth Kaifer、Hans-Jörg Himmel

  DOI：10.1002/zaac.201100005

  日期：2011.4

  Herein we report on the synthesis, structure, and optical properties of the fluorescent blue phosphazene dye 1,6‐bis(dimethylamino)‐2,5,7,10‐tetraazo‐1,6λ5‐diphosphapyrene, which was isolated as the unexpected product of the reaction between 1,4,5,8‐(tetraamino)naphthalene and [P(NMe2)3Br]Br. This dye, which turned out to be soluble in water and a range of organic solvents (including hexane, tetra

  本文我们的合成，结构报告，并且荧光蓝色磷腈的光学性质染料1,6-双（二甲基氨基）-2,5,7,10-四偶氮-1,6λ 5 -diphosphapyrene，将其分离为意外1,4,5,8-（四氨基）萘与[P（NMe 2）3 Br] Br之间的反应产物。该染料可溶于水和多种有机溶剂（包括己烷，四氢呋喃/石油醚，乙腈和乙醇），其结构通过XRD表征。分析了其吸收，发射光谱及其对pH变化的敏感性。实验工作得到了量子化学计算的补充，涉及到分离产物及其p K a途中可能的中间体 值。