1-Hydroxy-3.3-dimethyl-pyrrolidin | 3433-64-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂环丁烷
• 英文名称: 1-Hydroxy-3.3-dimethyl-pyrrolidin
• 英文别名: N-Hydroxy-3,3-dimethylpyrrolidin；3,3-dimethyl-pyrrolidin-1-ol；1-Hydroxy-3,3-dimethylpyrrolidine
• CAS: 3433-64-5
• 化学式: C₆H₁₃NO
• 分子量: 115.175
• InChiKey: HCTWEDGSZBQKJS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• QUINOLONE DERIVATIVES AS ANTIBACTERIALS
  申请人：JIANG Zhigan

  公开号：US20170217897A1

  公开（公告）日：2017-08-03

  This invention is in the field of medicinal chemistry and relates to compounds, and pharmaceutical compositions thereof, that inhibit bacterial gyrase. The compounds are useful as inhibitors of bacterial gyrase activity and bacterial infections, and have the structure of Formula (I) as further described herein. The invention further provides pharmaceutical compositions comprising a compound of Formula (I) and methods of using the compounds and compositions to treat bacterial infections.
• US9566312B2
  申请人：——

  公开号：US9566312B2

  公开（公告）日：2017-02-14