N-(4-ethylcyclohexyl)-5,6-dihydroxy-2-(1-methyl-1H-imidazol-4-yl)pyrimidine-4-carboxamide | 1407170-56-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并吡啶类
• 英文名称: N-(4-ethylcyclohexyl)-5,6-dihydroxy-2-(1-methyl-1H-imidazol-4-yl)pyrimidine-4-carboxamide
• 英文别名: N-(4-ethylcyclohexyl)-5-hydroxy-2-(1-methylimidazol-4-yl)-6-oxo-1H-pyrimidine-4-carboxamide
• CAS: 1407170-56-2
• 化学式: C₁₇H₂₃N₅O₃
• 分子量: 345.401
• InChiKey: BFQJECQYQGSBCA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  109
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• [EN] PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA<br/>[FR] COMPOSÉS DE PYRIMIDINONE ET MÉTHODES DE PRÉVENTION ET DE TRAITEMENT DE LA GRIPPE
  申请人：ST JUDE CHILDRENS RES HOSPITAL

  公开号：WO2012151567A1

  公开（公告）日：2012-11-08

  In one aspect, the invention relates to novel, broad-spectrum anti-viral, pyrimidinone compounds, methods of use, compositions and kits useful in treating and/or preventing influenza. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  在一个方面，该发明涉及新颖的、广谱抗病毒的嘧啶酮化合物，以及用于治疗和/或预防流感的方法、组合物和工具包。本摘要旨在作为在特定领域进行搜索的扫描工具，并不意味着对本发明的限制。
• PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA
  申请人：Webb Thomas R.

  公开号：US20140079666A1

  公开（公告）日：2014-03-20

  In one aspect, the invention relates to novel, broad-spectrum anti-viral, pyrimidinone compounds, methods of use, compositions and kits useful in treating and/or preventing influenza. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• US9328075B2
  申请人：——

  公开号：US9328075B2

  公开（公告）日：2016-05-03