N-(2'-methoxyethyl)phenazine-1-carboxamide | 1261237-08-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: N-(2'-methoxyethyl)phenazine-1-carboxamide
• 英文别名: N-(2-Methoxyethyl)-1-phenazinecarboxamide；N-(2-methoxyethyl)phenazine-1-carboxamide
• CAS: 1261237-08-4
• 化学式: C₁₆H₁₅N₃O₂
• 分子量: 281.314
• InChiKey: IHFHMXCOQKFSFQ-UHFFFAOYSA-N

物化性质

• 熔点：
  98-99 °C
• 沸点：
  560.1±25.0 °C(predicted)
• 密度：
  1.256±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为产物：
  描述：

  2-甲氧基乙胺 、 phenazine-1-carbonyl chloride 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 N-(2'-methoxyethyl)phenazine-1-carboxamide
  参考文献：
  名称：

  Phenazine-1-carboxylic acid derivatives: Design, synthesis and biological evaluation against Rhizoctonia solani Kuhn

  摘要：

  Rhizoctonia solani Kuhn is the pathogen that causes sheath blight and results in significant yield reduction in rice and in nearly 50 other crops. In order to develop a new fungicide effective against this pathogen, a series of structurally diverse phenazine-1-carboxylic acid derivatives, 2a, 2b, 2c, 2d, 2e, 2f, 2g, 2h, 2i, 2j, and 2k, were designed, synthesized and evaluated for their antifungal activity. The two most active compounds 2i and 2j were selected as lead compounds for further antifungal research. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.10.050