spiro[cyclopentanyl-1',2-(3-amino)-1H-quinoxaline] | 1241960-87-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: spiro[cyclopentanyl-1',2-(3-amino)-1H-quinoxaline]
• CAS: 1241960-87-1
• 化学式: C₁₂H₁₅N₃
• 分子量: 201.271
• InChiKey: SSIXDAVRFLPSBV-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  1-[(2-aminophenyl)amino]cyclopentanecarbonitrile 在 三乙胺 作用下， 以 对二甲苯 为溶剂， 反应 3.0h， 以70%的产率得到spiro[cyclopentanyl-1',2-(3-amino)-1H-quinoxaline]
  参考文献：
  名称：

  Application of Secondary Amines in the Synthesis of Some New Spiro Heterocyclic Compounds

  摘要：

  1-Anilinocycloalkanecarbonitriles 1a-c were prepared and reacted with active methylene reagents to give compounds 5a-c through 10a-c and reacted with different other reagents such as benzaldehyde, ethyl aminoacetate, ethyl mercaptoacetate, or hydrazine carbothioamide, which afforded the desired spiro heterocycles compounds 11a-c through 14a-c.

  DOI：

  10.1080/10426500802713283