2-propyl-5-fluoro-1,2,3,4-tetrahydro-6-naphthol | 315691-12-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: 2-propyl-5-fluoro-1,2,3,4-tetrahydro-6-naphthol
• 英文别名: 1-fluoro-6-propyl-5,6,7,8-tetrahydronaphthalen-2-ol
• CAS: 315691-12-4
• 化学式: C₁₃H₁₇FO
• 分子量: 208.276
• InChiKey: BSDLBWBZGBAZSL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-propyl-5-fluoro-1,2,3,4-tetrahydro-6-naphthol 在 四(三苯基膦)钯 作用下， 生成 2-propyl-5-fluoro-6-(3,4,5-trifluorophenyl)-1,2,3,4-tetrahydronaphthalene
  参考文献：
  名称：

  Design, Synthesis and Physical Properties of New Liquid Crystal Materials Having a Fluoro-Substituted Tetrahydronaphthalene Structure for Active Matrix LCD

  摘要：

  Liquid crystal materials having a fluoro-substituted tetralhydro-naphthalene structure were designed for active matrix LCD. 6-Aryl-5-fluoro-1,2,3,4-tetrahydronaphthalenes and 5,6-difluro-1,2,3,4-tetrahydronaphthalenes were prepared by regioselective fluorination and hydrogenation of 2-naphthols. 6-Aryl-5,7-difluoro-1,2,3,4-tetrahydronaphthalenes were synthesized from 5,7-difluoro-1,2,3,4-tetrahydronaphthalene-2-one. The liquid crystal mixture containing these compounds with very good co-solubility exhibits a wide nematic temperature range with low melting point and very large value of dielectric anisotropy. From these results these compounds are useful for design. of new liquid crystal mixtures for TFT-displays.

  DOI：

  10.1080/15421400490434973
• 作为产物：
  描述：

  6-丙基-2-萘酚 在 palladium on activated charcoal 氢气 、 N,N’-difluoro-2,2’-bipyridinium bis(tetrafluoroborate) 作用下， 生成 2-propyl-5-fluoro-1,2,3,4-tetrahydro-6-naphthol
  参考文献：
  名称：

  Design, Synthesis and Physical Properties of New Liquid Crystal Materials Having a Fluoro-Substituted Tetrahydronaphthalene Structure for Active Matrix LCD

  摘要：

  Liquid crystal materials having a fluoro-substituted tetralhydro-naphthalene structure were designed for active matrix LCD. 6-Aryl-5-fluoro-1,2,3,4-tetrahydronaphthalenes and 5,6-difluro-1,2,3,4-tetrahydronaphthalenes were prepared by regioselective fluorination and hydrogenation of 2-naphthols. 6-Aryl-5,7-difluoro-1,2,3,4-tetrahydronaphthalenes were synthesized from 5,7-difluoro-1,2,3,4-tetrahydronaphthalene-2-one. The liquid crystal mixture containing these compounds with very good co-solubility exhibits a wide nematic temperature range with low melting point and very large value of dielectric anisotropy. From these results these compounds are useful for design. of new liquid crystal mixtures for TFT-displays.

  DOI：

  10.1080/15421400490434973

文献信息

• Compound having tetrahydronaphthalene skeleton and liquid crystal composition containing same
  申请人：Dainippon Ink and Chemicals, Inc.

  公开号：US06746728B1

  公开（公告）日：2004-06-08

  A tetrahydronaphthalene derivative represented by the general formula (I) and a liquid crystal composition containing the same. A compound represented by the general formula (I) shows superior liquid crystallinity and co-solubility with conventional liquid crystal compounds and compositions. Furthermore, addition of such a compound enables the threshold voltage to be significantly reduced with almost no deleterious effect on the responsiveness. In addition, a compound of the present invention can also be easily produced industrially, is colorless, and is chemically stable. Consequently, liquid crystal compositions containing such a compound are extremely useful as liquid crystals, and are particularly suitable for liquid crystal displays requiring a wide operating temperature range, low voltage driving and a high response speed.

  一种由通式(I)表示的四氢萘衍生物及其所含的液晶组合物。通式(I)所表示的化合物具有优越的液晶性和与传统液晶化合物和组合物的共溶性。此外，添加这种化合物可以显著降低阈值电压，几乎不会对响应性产生不良影响。此外，本发明的化合物也可以在工业上轻松生产，无色，化学稳定。因此，含有这种化合物的液晶组合物非常有用作为液晶，特别适用于需要广泛操作温度范围、低电压驱动和高响应速度的液晶显示器。
• COMPOUND HAVING TETRAHYDRONAPHTHALENE SKELETON AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME
  申请人：DAINIPPON INK AND CHEMICALS, INC.

  公开号：EP1191008B1

  公开（公告）日：2005-02-09
• US6746728B1
  申请人：——

  公开号：US6746728B1

  公开（公告）日：2004-06-08
• Design, Synthesis and Physical Properties of New Liquid Crystal Materials Having a Fluoro-Substituted Tetrahydronaphthalene Structure for Active Matrix LCD
  作者：Tetsuo Kusumoto、Yoshitaka Saito、Yutaka Nagashima、Makoto Negishi、Sadao Takehara、Yoshinori Iwashita、Kiyofumi Takeuchi、Haruyoshi Takatsu、Corneria Pithart、Rainer Frings、Artur Lachowicz、Gerwald Grahe

  DOI：10.1080/15421400490434973

  日期：2004.1

  Liquid crystal materials having a fluoro-substituted tetralhydro-naphthalene structure were designed for active matrix LCD. 6-Aryl-5-fluoro-1,2,3,4-tetrahydronaphthalenes and 5,6-difluro-1,2,3,4-tetrahydronaphthalenes were prepared by regioselective fluorination and hydrogenation of 2-naphthols. 6-Aryl-5,7-difluoro-1,2,3,4-tetrahydronaphthalenes were synthesized from 5,7-difluoro-1,2,3,4-tetrahydronaphthalene-2-one. The liquid crystal mixture containing these compounds with very good co-solubility exhibits a wide nematic temperature range with low melting point and very large value of dielectric anisotropy. From these results these compounds are useful for design. of new liquid crystal mixtures for TFT-displays.