8-benzyl-2-(4-hydroxy-benzyl)-6-(4-methoxy-phenyl)-7H-imidazo[1,2-a]pyrazin-3-one | 124469-79-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并吡嗪类
• 英文名称: 8-benzyl-2-(4-hydroxy-benzyl)-6-(4-methoxy-phenyl)-7H-imidazo[1,2-a]pyrazin-3-one
• 英文别名: 8-benzyl-2-[(4-hydroxyphenyl)methyl]-6-(4-methoxyphenyl)-7H-imidazo[1,2-a]pyrazin-3-one
• CAS: 124469-79-0
• 化学式: C₂₇H₂₃N₃O₃
• 分子量: 437.498
• InChiKey: XJWAQGCSGJBIOH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  33
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  74.2
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• NOVEL COELENTERAZINE COMPOUNDS AND METHODS OF USE
  申请人：PROLUME, LTD.

  公开号：US20170217969A1

  公开（公告）日：2017-08-03

  Calcium reacting photoproteins are a class of self-illuminating proteins that emit light upon contact with calcium. Fluorescent Proteins are small proteins that change the color of light when excited. Fluorescent Proteins and Calcium Activated Photoproteins can be used to enhance, dazzle, amaze, startle, and otherwise entertain an audience by their direct application on to the audience, surroundings, the actors, or sprayed on settings as in the newer 4D movies. The disclosure comprises novel Coelenterazine compounds and methods of use, including a simple delivery device for the photoprotein to create unique and novel cinematic, theatrical, stage, movie and musical concert optical effects by their luminous reaction upon contact with surfaces that contain calcium. Calcium is ubiquitous in and on most surfaces and in the environment; it is this unique property of calcium that makes this a novel use of the photoproteins for entertainment.

  钙反应光蛋白是一类自发发光的蛋白质，与钙接触时会发出光。荧光蛋白是一种小型蛋白质，当受到光的激发时会改变光的颜色。荧光蛋白和钙活化光蛋白可以通过直接应用于观众、环境、演员或喷洒在设置中（如新型4D电影）来增强、令人惊叹、震撼、惊艳并提供娱乐效果。本发明涉及新型荧光素化合物及其使用方法，包括一种简单的输送装置，可将光蛋白输送到含有钙的表面上，通过其与钙的反应产生独特的、新颖的电影、戏剧、舞台、音乐会光学效果，这是一种娱乐性的新用途。钙普遍存在于大多数表面和环境中，正是这种钙的独特性质使得光蛋白在娱乐方面具有新颖的应用价值。
• Chemiluminescent methods and reagents for analyte detection
  申请人：Wang Tianxin

  公开号：US20110097753A1

  公开（公告）日：2011-04-28

  The present invention relates to chemiluminescent method and regent to detect analyte. One aspect of the current invention relates to using enzyme substrate that can be cleaved by target enzyme to release chemiluminescent compound giving light signal for the detection of varieties of target enzymes. Another aspect of the current invention relates to use chemiluminescent enzyme coupled with analyte binding molecules to detect specific analyte molecules in a homogenous phase.
• CHEMILUMINESCENT METHODS AND REAGENTS FOR ANALYTE DETECTION
  申请人：Wang Tianxin

  公开号：US20160362388A1

  公开（公告）日：2016-12-15

  The present invention relates to chemiluminescent method and regent to detect analyte. One aspect of the current invention relates to using enzyme substrate that can be cleaved by target enzyme to release chemiluminescent compound giving light signal for the detection of varieties of target enzymes. Another aspect of the current invention relates to use chemiluminescent enzyme coupled with analyte binding molecules to detect specific analyte molecules in a homogenous phase.
• US9399657B2
  申请人：——

  公开号：US9399657B2

  公开（公告）日：2016-07-26