2,3-Dimethylimidazo<1,2-a>-pyrimidin | 45880-46-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并[1，2-a]嘧啶
• 英文名称: 2,3-Dimethylimidazo<1,2-a>-pyrimidin
• 英文别名: 2,3-dimethyl-imidazo[1,2-a]pyrimidine；2,3-Dimethylimidazo[1,2-a]pyrimidine
• CAS: 45880-46-4
• 化学式: C₈H₉N₃
• 分子量: 147.18
• InChiKey: ICAGBVAZYDIBBF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  30.2
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS
  申请人：Ritzén Andreas

  公开号：US20100016303A1

  公开（公告）日：2010-01-21

  This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.

  这项发明涉及一类PDE10A酶抑制剂化合物。该发明提供了一种包含所述发明化合物的治疗有效量和药学可接受载体的药物组合物。本发明还提供了制备式I化合物的方法。本发明还提供了一种治疗患有神经退行性疾病的受试者的方法，包括向受试者投予式I化合物的治疗有效量。本发明还提供了一种治疗患有药物成瘾的受试者的方法，包括向受试者投予式I化合物的治疗有效量。本发明还提供了一种治疗患有精神障碍的受试者的方法，包括向受试者投予式I化合物的治疗有效量。
• [EN] FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS<br/>[FR] COMPOSÉS HÉTÉROCYCLIQUES FUSIONNÉS ET LEUR UTILISATION EN TANT QU'AGENTS DE LUTTE CONTRE LES ORGANISMES NUISIBLES
  申请人：PI INDUSTRIES LTD

  公开号：WO2021033141A1

  公开（公告）日：2021-02-25

  The present invention discloses a fused heterocyclic compound of formula (I) wherein, R1, G1, G2, G3, G4, A1, A2, Q, n and Z are as defined in the detailed description. The present invention further discloses methods for their preparation and use of the compounds of formula (I) as a pest control agent.

  本发明揭示了一种具有化学式（I）的融合杂环化合物，其中，R1、G1、G2、G3、G4、A1、A2、Q、n和Z的定义如详细说明中所述。本发明还揭示了制备这些化合物的方法，并将化合物（I）用作杀虫剂的用途。
• ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME
  申请人：Samsung Display Co., Ltd.

  公开号：US20210057657A1

  公开（公告）日：2021-02-25

  An organometallic compound is represented by Formula 1. An organic light-emitting device includes: a first electrode; a second electrode facing the first electrode; an organic layer between the first electrode and the second electrode and comprising an emission layer; and the organometallic compound represented by Formula 1. In Formula 1, each substituent is the same as described herein.

  一个含有有机金属化合物的化学式为Formula 1。一种有机发光器件包括：第一电极；面向第一电极的第二电极；位于第一电极和第二电极之间的有机层，包括一个发射层；以及化学式为Formula 1的有机金属化合物。在Formula 1中，每个取代基与此处描述的相同。
• AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME
  申请人：SAMSUNG DISPLAY CO. LTD.

  公开号：US20190055187A1

  公开（公告）日：2019-02-21

  An amine-based compound represented by Formula 1, in which one of R 1 to R 10 is a group represented by Formula 2, and an organic light-emitting device including the same are provided: When the amine-based compound is included in an organic light-emitting device as a hole transport material, the device may exhibit excellent I-V-L characteristics, including a low driving voltage, improved efficiency, and improved lifespan.

  提供了由公式1表示的一种胺基化合物，其中R1至R10中的一个是由公式2表示的基团，并且包括该化合物的有机发光器件：当将该胺基化合物作为空穴传输材料包含在有机发光器件中时，该器件可能表现出优异的I-V-L特性，包括低驱动电压、提高效率和延长寿命。
• AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE AMINE-BASED COMPOUND
  申请人：Samsung Display Co., Ltd.

  公开号：US20190115543A1

  公开（公告）日：2019-04-18

  Provided is an amine-based compound represented by one of Formulae 1-1 and 1-2. An organic light-emitting device includes: a first electrode; a second electrode facing the first electrode; and an organic layer disposed between the first electrode and the second electrode, where the organic layer includes an emission layer and at least one amine-based compound described above.

  提供的是由公式1-1和1-2中的一种表示的胺基化合物。一种有机发光器件包括：第一电极；面向第一电极的第二电极；以及位于第一电极和第二电极之间的有机层，其中有机层包括一个发射层和至少一个上述描述的胺基化合物。

表征谱图