磷酸异癸基二苯酯 | 29761-21-5

• 物质功能分类: 有机原料 - 无机酸酯
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 中文名称: 磷酸异癸基二苯酯
• 中文别名: 磷酸二苯基异癸酯；磷酸二苯基异癸酯(D.P.D.P)
• 英文名称: isodecyl diphenyl phosphate
• 英文别名: IDDP；iso-decyl diphenyl phosphate；diphenyl isodecyl phosphate；8-methylnonyl diphenyl phosphate
• CAS: 29761-21-5
• 化学式: C₂₂H₃₁O₄P
• 分子量: 390.459
• InChiKey: RYUJRXVZSJCHDZ-UHFFFAOYSA-N

物化性质

• 熔点：
  -34.9°C
• 沸点：
  245 (dec 10mm)
• 密度：
  1.070 g/cm3
• 闪点：
  465
• 溶解度：
  可溶于氯仿（少许）、甲醇（少许）
• LogP：
  6.11 at 25℃
• 物理描述：
  Isodecyl diphenyl phosphate is a viscous clear colorless liquid. (NTP, 1992)
• 蒸汽压力：
  1.6X10-5 mm Hg at 25 °C (est)

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  27
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

ADMET

毒理性

• 解毒与急救

一个昏迷的病人，全身出汗，瞳孔缩小，衣物或呼吸中有杀虫剂的气味，并且肌肉出现颤动，这是有机磷中毒的典型表现。... 管理的具体步骤包括以下内容。1. 去污。... 2. 气道。如有必要，建立气道。... 3. 呼吸状态。事实上，这些病人由于多种原因经常出现呼吸窘迫。... 4. 心脏监测。... 5. 胆碱酯酶水平。... 6. 普瑞洛昔姆。普瑞洛昔姆是有机磷中毒的首选治疗方法，应几乎用于所有临床上有显著有机磷中毒的病人，特别是那些肌肉颤动和虚弱的病人。... 7. 阿托品。阿托品是有机磷中毒的生理性拮抗剂。当怀疑有机磷中毒时，应基于临床情况给予试验剂量的阿托品。/有机磷中毒/

A comatose patient who is diaphoretic, has pinpoint pupils and the odor of an insecticide on clothing or breath, and is noted to have muscle fasciculations represents the classic presentation of organophosphate poisoning. ... Specific steps in management include the following. 1. Decontamination. ... 2 Airway. Establish an airway if necessary. ... 3. Respiratory Status. Respiratory distress, in fact, is commonly found in these patients from multiple causes. ... 4. Cardiac Monitoring. ... 5. Cholinesterase Level. ... 6. Pralidoxime. Pralidoxime is the treatment of choice for organophosphate poisoning and should be used for nearly all patients with clinically significant orgnophosphate poisoning,particularly whose patients with muscular fasciculations and weakness. ... 7. Atropine. Atropine is the physiologic antidote for organophosphate poisoning. A trial dose of atropine should be instituted on clinical ground when one suspects organophosphate intoxication. /Organophosphate poisoning/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 非人类毒性摘录

有机磷化合物的中毒症状是由于乙酰胆碱积聚，因此导致副交感神经系统过度兴奋。通常将它们分为三个类别：毒蕈碱样、烟碱样和中枢样。毒蕈碱样症状包括过度流涎、流泪、出汗和鼻涕。瞳孔缩小、呼吸困难、呕吐、腹泻和尿频...烟碱样效应包括肌肉纤维颤动、无力和麻痹。中枢神经系统效应包括紧张、焦虑、共济失调、惊厥和昏迷。死亡是由于呼吸衰竭，有时是心脏骤停。不同有机磷化合物产生的症状差别不大，但吸收途径可能会更多地影响一个系统而不是另一个。/有机磷化合物/

The signs of poisoning due to organophosphorus cmpd are those due to accumulation of acetylcholine & hence overstimulation of parasympathetic nervous system. It is usual to divide them under 3 headings: muscarinic, nicotinic & central. Muscarinic signs ... consist of hypersalivation, lacrimation, sweating & nasal discharge. Miosis, dyspnea, vomiting, diarrhea & frequency of urination ... Nicotinic effects consist of fasciculation of muscles, weakness & paralysis. Central nervous system effects include nervousness, apprehension, ataxia, convulsions & coma. Death is due to resp failure, or sometimes cardiac arrest. There is little difference between signs produced by different organophosphorus compounds, but route of absorption may influence one system more than another. /Organophosphorus cmpd/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 生态毒性值

LC50 Lepomis macrochirus 6700 ppm/96小时，静态生物测试在23°C的淡水中进行，24小时后施加轻微曝气。

LC50 Lepomis macrochirus 6700 ppm/96 hr, static bioassay in fresh water at 23 °C, mild aeration applied after 24 hr.

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 生态毒性值

LC50 Menidia beryllina 1400 ppm/96小时，静态生物测试在23°C的人工海水中进行，24小时后施加轻微曝气。

LC50 Menidia beryllina 1400 ppm/96 hr, static bioassay in synthetic seawater at 23 °C, mild aeration applied after 24 hr.

来源:Hazardous Substances Data Bank (HSDB)

安全信息

• TSCA：
  TSCA listed
• 危险等级：
  9
• 危险品运输编号：
  UN 3082
• 包装等级：
  III
• 储存条件：
  2-8°C，储存在惰性气体中。

上下游信息

• 上游原料

  中文名称	英文名称	CAS号	化学式	分子量
  磷酸三苯酯	phosphoric acid triphenyl ester	115-86-6	C18H15O4P	326.288

反应信息

• 作为产物：
  描述：

  异十醇 、 磷酸三苯酯 、 二氯磷酸苯酯 、 氯磷酸二苯酯 在 magnesium chloride 作用下， 20.0~120.0 ℃ 、13.33 kPa 条件下， 反应 4.0h， 生成 磷酸异癸基二苯酯 、 磷酸二苯酯 、 isodecyl chloride 、 磷酸二异癸基苯酯
  参考文献：
  名称：

  Process to prepare alkyl phenyl phosphates

  摘要：

  本发明涉及一种制备二烷基单苯酸酯、单烷基二苯酸酯或其混合物的方法，其中在无溶剂存在的情况下，以路易斯酸催化剂为催化剂，在40至200°C温度和0至1巴压力下，将二氯单苯酸酯和/或单氯二苯酸酯与脂肪族醇反应。本发明还涉及从上述方法获得的单烷基二苯酸酯和二烷基单苯酸酯的混合物以及将这种混合物用作增塑剂和/或阻燃剂的用途。

  公开号：

  EP1526137A1

文献信息

• AMIDINE GROUP - OR GUANIDINE GROUP - CONTAINING SILANE
  申请人：SIKA TECHNOLOGY AG

  公开号：US20170081348A1

  公开（公告）日：2017-03-23

  A silane of the formula (I) containing at least one aliphatic amidine group- or guanidine group-containing alkoxy group, to a method for producing same, to conversion products thereof, and to the use thereof as a catalyst in curable compositions, in particular based on silane group-containing polymers. The silane of the formula (I) is largely odorless and non-volatile at room temperature. The silane accelerates the hydrolysis and condensation reaction of silane groups very effectively without impairing the storage stability of silane group-containing polymers. Additionally, the silane is very tolerable in silane group-containing compositions, whereby such compositions are not prone to separate, migrate, or evaporate the catalyst.

  公式（I）中含有至少一个脂肪族酰胺基或含有酰胺基的胍基的烷氧基团的硅烷，以及生产同类产物的方法，以及将其用作固化组合物中的催化剂的用途，特别是基于含硅烷基的聚合物。公式（I）中的硅烷在室温下基本无味且不挥发。该硅烷有效加速硅烷基的水解和缩合反应，而不会影响含硅烷基聚合物的储存稳定性。此外，该硅烷在含硅烷基的组合物中具有很高的耐受性，因此这些组合物不容易分离、迁移或挥发出催化剂。
• HYDROXYSILANE AND POLYMER CONTAINING SILANE GROUPS
  申请人：SIKA TECHNOLOGY AG

  公开号：US20160102110A1

  公开（公告）日：2016-04-14

  Special hydroxysilanes, which can be obtained by reacting β-(3,4-epoxycyclohexyl)alkyltrialkoxysilanes with secondary amines, and adducts of the hydroxysilanes in the form of polymers containing silane groups. The hydroxysilanes can be produced having high purity in a simple process and are very stable in storage after production. The polymers containing silane groups that can be obtained by means of the hydroxysilanes have advantageous properties. The polymers enable moisture-curing compositions, which contain no isocyanate groups and which are suitable as elastic adhesives and sealants.

  特殊的羟基硅烷可以通过将β-(3,4-环氧环己基)烷基三烷氧基硅烷与二级胺发生反应获得，并以含硅基团的聚合物形式存在。这些羟基硅烷可以通过简单的工艺制备高纯度，并在生产后储存时非常稳定。通过这些羟基硅烷可以获得具有优越性能的含硅基团的聚合物。这些聚合物使得含有羟基硅烷的水固化组合物成为可能，这些组合物不含异氰酸酯基团，适用于弹性胶粘剂和密封剂。
• TETRAHYDROFURAN DERIVATIVES AND USE THEREOF AS PLASTICIZERS
  申请人：BASF SE

  公开号：US20160075671A1

  公开（公告）日：2016-03-17

  The invention relates to tetrahydrofuran derivatives of general formula (I), wherein X stands for *—(C═O)—O—, *—(CH2)n-O—, or *—(CH2)n-O—(C═O)—, wherein * represents the point of bonding to the tetrahydrofuran ring and n has the value 0, 1, or 2; and R1 and R2 are selected independently of each other from among C4-C5 alkyl and C5-C6 cycloalkyl, wherein the cycloalkyl groups are unsubstituted or can be substituted by at least one C1-C10 alkyl group, a plasticizer composition that contains said tetrahydrofuran derivatives, molding masses that contain a thermoplastic polymer or an elastomer and such a tetrahydrofuran derivative. The invention further relates to a method for producing said tetrahydrofuran derivatives, and to the use of said tetrahydrofuran derivatives

  该发明涉及一般式(I)的四氢呋喃衍生物，其中X代表*—(C═O)—O—、*—(CH2)n-O—或*—(CH2)n-O—(C═O)—，其中*代表与四氢呋喃环的连接点，n的值为0、1或2；R1和R2分别从C4-C5烷基和C5-C6环烷基中独立选择，其中环烷基可以是未取代的或可以被至少一个C1-C10烷基基团取代，含有所述四氢呋喃衍生物的增塑剂组合物，含有热塑性聚合物或弹性体以及该四氢呋喃衍生物的成型物料。该发明还涉及制备所述四氢呋喃衍生物的方法，以及使用所述四氢呋喃衍生物。
• SECONDARY AMINOSILANES
  申请人：SIKA TECHNOLOGY AG

  公开号：US20130281562A1

  公开（公告）日：2013-10-24

  The present disclosure invention relates to novel secondary aminosilanes, a method for producing same, and the use thereof. The secondary aminosilanes can be produced from readily available reactants in a simple manner. The secondary aminosilanes are characterized for example by a low viscosity and are well suited for producing silane-functional polymers that have a low viscosity, fast curing, and good thermal stability.

  本公开的发明涉及新型二次氨基硅烷、其生产方法以及应用。这些二次氨基硅烷可以从易得的反应物中简单地生产出来。这些二次氨基硅烷具有低粘度等特点，非常适合用于生产具有低粘度、快速固化和良好热稳定性的硅烷功能聚合物。
• LATENT CURING AGENT AND CURABLE POLYURETHANE COMPOSITION
  申请人：SIKA TECHNOLOGY AG

  公开号：US20200140599A1

  公开（公告）日：2020-05-07

  A compound of formula (I) having advantageous properties when used as a latent curing agent for compositions containing isocyanate groups, and to compositions containing the compound of formula (I). The compound of formula (I) is odourless, is liquid and has comparatively low viscosity at room temperature and is stable in storage together with isocyanates. It makes possible odourless single-component polyurethane compositions which have good stability in storage, do not produce bubbles when cured in the presence of moisture, and cause no problematic odour emissions, giving a cured elastic material having good mechanical properties, good heat stability, a surprisingly non-adhesive surface and little tendency towards plasticizer migration.

  具有优越特性的化合物，其化学式为（I），在含异氰酸基团的组合物中作为潜在固化剂使用时具有优势，并且包含化合物（I）的组合物。化合物的化学式（I）无味，液态，在室温下粘度相对较低，在与异氰酸酯一起储存时稳定。它使得可能制备无味的单组分聚氨酯组合物，在储存中具有良好稳定性，在存在湿气时固化时不产生气泡，并且不会产生有问题的气味排放，从而获得具有良好机械性能、良好热稳定性、惊人的非粘附表面和少量塑化剂迁移倾向的固化弹性材料。