Acetic acid 3''-hydroxy-2,2',3',2''-tetramethoxy-[1,1';4',1'']ternaphthalen-3-yl ester | 328235-15-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Acetic acid 3''-hydroxy-2,2',3',2''-tetramethoxy-[1,1';4',1'']ternaphthalen-3-yl ester
• 英文别名: [4-[4-(3-Hydroxy-2-methoxynaphthalen-1-yl)-2,3-dimethoxynaphthalen-1-yl]-3-methoxynaphthalen-2-yl] acetate
• CAS: 328235-15-0
• 化学式: C₃₆H₃₀O₇
• 分子量: 574.63
• InChiKey: UFVGXFOWIZHVRL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  43
• 可旋转键数：
  8
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  83.4
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  Acetic acid 3''-hydroxy-2,2',3',2''-tetramethoxy-[1,1';4',1'']ternaphthalen-3-yl ester 在 α-苯乙胺 、 copper dichloride 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 23.0h， 以38%的产率得到[4-[4-[4-[4-[4-(3-Acetyloxy-2-methoxynaphthalen-1-yl)-2,3-dimethoxynaphthalen-1-yl]-2-hydroxy-3-methoxynaphthalen-1-yl]-3-hydroxy-2-methoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-3-methoxynaphthalen-2-yl] acetate
  参考文献：
  名称：

  Configurationally defined sexi- and octinaphthalene derivatives: synthesis and optical properties

  摘要：

  The copper mediated oxidative coupling of optically active quaternaphthalenes having a 2-hydroxynaphthyl moiety gave configurationally defined optically active octinaphthalenes. The absolute configuration was determined by comparison with products of [6+2] coupling. The CD spectra of bi-, ter-, quater-, sexi- and octinaphthalenes suggested that the absolute configuration of the chiral axis could be deduced from the intensity of their Cotton effects. (C) 2004 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tet.2004.03.055
• 作为产物：
  描述：

  Acetic acid 3''-benzyloxy-3',2''-dihydroxy-2,2'-dimethoxy-[1,1';4',1'']ternaphthalen-3-yl ester 在 palladium on activated charcoal 氢气 作用下， 生成 Acetic acid 3''-hydroxy-2,2',3',2''-tetramethoxy-[1,1';4',1'']ternaphthalen-3-yl ester
  参考文献：
  名称：

  Synthesis of Configurationally Defined Sexi- and Octinaphthalene Derivatives

  摘要：

  [GRAPHICS]Configurationally defined optically active octinaphthalenes were synthesized using the oxidative coupling of optically active quaternaphthalenes with a 2-hydroxynaphthol moiety as a key reaction. The absolute configuration was determined by comparison with products of [6 + 2] coupling.

  DOI：

  10.1021/ol006843c