2,3-diethyl-imidazo[1,2-a]pyridine | 34172-76-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并吡啶类
• 英文名称: 2,3-diethyl-imidazo[1,2-a]pyridine
• 英文别名: 2,3-Diethylimidazo[1,2-a]pyridine
• CAS: 34172-76-4
• 化学式: C₁₁H₁₄N₂
• 分子量: 174.246
• InChiKey: HJZIWIYQMWJTDS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  17.3
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• BICYCLIC AGONISTS OF GPR131 AND USES THEREOF
  申请人：SONG Jiangao

  公开号：US20130059845A1

  公开（公告）日：2013-03-07

  The present disclosure relates to compounds that act as agonists of, or otherwise modulate the activity of, GPR131 and to their use in the treatment of various diseases. In particular embodiments, the structure of the compounds is given by Formula I: wherein the variables are as described herein. Related compositions, formulations and methods for the preparation of compounds of formula I are also described.

  本公开涉及作为GPR131的激动剂或以其他方式调节其活性的化合物，以及它们在治疗各种疾病中的应用。在特定实施例中，化合物的结构由公式I给出：其中变量如本文所述。还描述了与公式I化合物的相关组合物、配方和制备方法。
• CHEMICAL COMPOUNDS
  申请人：Gudmundsson Kristjan

  公开号：US20100227880A1

  公开（公告）日：2010-09-09

  The present invention provides compounds of formula (I): including salts, solvates, and pharmaceutically acceptable derivatives thereof, pharmaceutical formulations containing them, processes for their preparation, and methods of treatment using them.

  本发明提供了式(I)的化合物，包括其盐、溶剂合物和药学上可接受的衍生物，含有它们的制药组合物，其制备方法，以及使用它们的治疗方法。
• Heterocyclic compounds and uses thereof
  申请人：Infinity Pharmaceuticals, Inc.

  公开号：US10919914B2

  公开（公告）日：2021-02-16

  Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.

  本文描述了调节激酶活性（包括 PI3 激酶活性）的化合物和药物组合物，以及治疗与激酶活性（包括 PI3 激酶活性）相关的疾病和病症的化合物、药物组合物和方法。
• COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE
  申请人：JUNG Ho-Kuk

  公开号：US20130299794A1

  公开（公告）日：2013-11-14

  A compound for an organic optoelectronic device, the compound being represented by the following Chemical Formula 1:
• HETEROCYCLIC COMPOUNDS AND USES THEREOF
  申请人：Infinity Pharmaceuticals, Inc.

  公开号：US20190135833A1

  公开（公告）日：2019-05-09

  Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.