5-(2-furanyl)-2-methylbenzoxazole | 99969-96-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶唑类
• 英文名称: 5-(2-furanyl)-2-methylbenzoxazole
• 英文别名: 5-(Furan-2-yl)-2-methylbenzoxazole；5-Fur-2-yl-2-methyl-benzoxazol；5-(furan-2-yl)-2-methyl-1,3-benzoxazole
• CAS: 99969-96-7
• 化学式: C₁₂H₉NO₂
• 分子量: 199.209
• InChiKey: VAEIMTPWOQIEAI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  39.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5-氯-2-甲基苯并恶唑 、 2-furanylboronic acid MIDA ester 在 2-双环己基膦-2',6'-二甲氧基联苯 、 palladium diacetate 、 potassium phosphate 、 水 作用下， 以 1,4-二氧六环 为溶剂， 反应 6.67h， 以99%的产率得到5-(2-furanyl)-2-methylbenzoxazole
  参考文献：
  名称：

  Knapp, David M.; Gillis, Eric P.; Burke, Martin D., Journal of the American Chemical Society, 2009, vol. 131, p. 6961 - 6963

  摘要：

  DOI：

文献信息

• Dye compounds and photographic elements containing such dyes
  申请人：Eastman Kodak Company

  公开号：US05492802A1

  公开（公告）日：1996-02-20

  A silver halide photographic element comprising a sensitizing dye of the formula: ##STR1## wherein: X1, X2, n, L, L2, R1 and R2 are as defined in the specification; Z1 represents Ar1-(L1) m, where Ar1 is a substituted or unsubstituted aromatic group, L1 is a linking group, m is 0 or 1, and the LOGP(A) of a molecule having a structure A corresponding to a portion of the dye ##STR2## is no more than 90% of LOGP(A'), where A' is the same as A except Z1 is replaced with unsubstituted phenyl, provided that L1 is not --CO-- when X1 or X2 is S or Se; and W1 is a counterion as needed to balance the charge of the molecule.

  一种银卤化物感光元件，包括下式的感光染料：##STR1## 其中：X1、X2、n、L、L2、R1和R2如规范所定义；Z1表示Ar1-(L1) m，其中Ar1是取代或未取代的芳香基团，L1是连接基团，m为0或1，且具有结构A的分子的LOGP（A）不超过LOGP（A'）的90％，其中A'与A相同，除Z1被未取代的苯基替换外，前提是当X1或X2为S或Se时，L1不是--CO--; W1是需要平衡分子电荷的计数离子。
• Slow Release of Organoboronic Acids in Cross-Coupling Reactions
  申请人：Burke Martin D.

  公开号：US20100121062A1

  公开（公告）日：2010-05-13

  A method of performing a chemical reaction includes reacting a compound selected from the group consisting of an organohalide and an organo-pseudohalide, and a protected organoboronic acid represented by formula (I) in a reaction mixture: R 1 —B-T   (I); where R 1 represents an organic group, T represents a conformationally rigid protecting group, and B represents boron having sp 3 hybridization. When unprotected, the corresponding organoboronic acid is unstable by the boronic acid neat stability test. The reaction mixture further includes a base having a pK B of at least 1 and a palladium catalyst. The method further includes forming a cross-coupled product in the reaction mixture.

  一种化学反应的方法包括在反应混合物中反应从有机卤化物和有机伪卤化物中选择的化合物，以及由公式（I）表示的受保护的有机硼酸：R1—B-T  （I）;其中，R1表示有机基团，T表示构象刚性保护基团，B表示具有sp3杂化的硼。当未受保护时，相应的有机硼酸在硼酸稳定性测试中不稳定。反应混合物还包括具有至少1的pKB值和钯催化剂的碱。该方法还包括在反应混合物中形成交叉偶联产物。
• Furan or pyrrole substituted dye compounds and silver halide photographic elements containing such dyes
  申请人：EASTMAN KODAK COMPANY

  公开号：EP0599383A1

  公开（公告）日：1994-06-01

  Spectral sensitizing dyes, and silver halide photographic elements incorporating them, which dyes have the formula: wherein:    X1 and X2 each independently represent the atoms necessary to complete a 5- or 6-membered heterocyclic nucleus (preferably benzo-condensed), and X1 may be further substituted and X2 substituted or unsubstituted;    n is a positive integer from 1 to 4,    p and q each independently represents 0 or l,    each L independently represents a substituted or unsubstituted methine group,    R1 and R2 each independently represents substituted or unsubstituted aryl or substituted or unsubstituted alkyl,    Z1 represents a substituted or unsubstituted pyrrole or furan containing group;    W1 is a counterion as needed to balance the charge of the molecule.

  光谱感光染料和含有这些染料的卤化银感光元件，这些染料的化学式为 其中 X1和X2各自独立地代表完成5或6元杂环核（最好是苯并缩合）所需的原子，X1可进一步取代，X2可取代或未取代； n 是 1 至 4 的正整数、 p 和 q 各自独立地代表 0 或 l、 每个 L 独立地代表一个取代或未取代的甲基、 R1 和 R2 各自独立地代表取代或未取代的芳基或取代或未取代的烷基、 Z1 代表取代或未取代的含吡咯或呋喃的基团； W1 是平衡分子电荷所需的反离子。
• Silver halide photographic elements containing furan or pyrrole substituted dye compounds
  申请人：EASTMAN KODAK COMPANY

  公开号：EP0599383B1

  公开（公告）日：2001-02-28
• US5418126A
  申请人：——

  公开号：US5418126A

  公开（公告）日：1995-05-23