2-(2-Methyloxiran-2-yl)-1-benzofuran | 64481-23-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 英文名称: 2-(2-Methyloxiran-2-yl)-1-benzofuran
• CAS: 64481-23-8
• 化学式: C₁₁H₁₀O₂
• 分子量: 174.199
• InChiKey: YVYOGGKPLCYAPS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  25.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(2-Methyloxiran-2-yl)-1-benzofuran 在 三氟化硼乙醚 作用下， 以 四氢呋喃 为溶剂， 生成 2-(benzofuran-2-yl)propanal
  参考文献：
  名称：

  Synthesis of chiral butenolides using amino-thiocarbamate-catalyzed asymmetric bromolactonization

  摘要：

  The asymmetric cyclization of 4,4-disubstituted 3-butenoic acids is studied. Amino-thiocarbamates are used as the catalysts and N-bromosuccinimide is used as the stoichiometric halogen source. The resulting gamma-butanolide products are readily converted into the corresponding gamma-butenolides (up to 58% ee) derivatives in one-pot. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.01.009
• 作为产物：
  描述：

  2-乙酰基苯并呋喃 、 trimethylsulfonium iodide 在 sodium hydride 作用下， 以 四氢呋喃 、 二甲基亚砜 为溶剂， 生成 2-(2-Methyloxiran-2-yl)-1-benzofuran
  参考文献：
  名称：

  Synthesis of chiral butenolides using amino-thiocarbamate-catalyzed asymmetric bromolactonization

  摘要：

  The asymmetric cyclization of 4,4-disubstituted 3-butenoic acids is studied. Amino-thiocarbamates are used as the catalysts and N-bromosuccinimide is used as the stoichiometric halogen source. The resulting gamma-butanolide products are readily converted into the corresponding gamma-butenolides (up to 58% ee) derivatives in one-pot. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.01.009

文献信息

• KUTSUMA T.; NAGAYAMA I.; OKAZAKI T.; SAKAMOTO T.; AKABOSHI S., HETEROCYCLES, 1977, 8, SPEC. ISSUE, 397-401
  作者：KUTSUMA T.、 NAGAYAMA I.、 OKAZAKI T.、 SAKAMOTO T.、 AKABOSHI S.

  DOI：——

  日期：——
• [EN] NOVEL TRIAZOLE COMPOUNDS FOR CONTROLLING PHYTOPATHOGENIC HARMFUL FUNGI<br/>[FR] NOUVEAUX COMPOSÉS DE TRIAZOLE POUR CONTRÔLER DES CHAMPIGNONS NOCIFS PHYTOPATHOGÈNES
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2016156282A1

  公开（公告）日：2016-10-06

  The present invention relates to a novel triazole compound and its salts and N-oxides, a composition comprising such compound, a method for curatively or preventively controlling phytopathogenic harmful fungi of plants or crops comprising the step of applying such compound or composition, to the use of such compound or such composition to control phytopathogenic harmful fungi and to a seed that has been treated with such a compound or such a composition. Further the present invention relates to novel epoxides which are useful intermediates in the synthesis of the triazole compounds of the invention.