2-{[(1E)-(2-hydroxyphenyl)methylene]amino}-2-methylpropane-1,3-diol | 1164273-65-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-{[(1E)-(2-hydroxyphenyl)methylene]amino}-2-methylpropane-1,3-diol
• 英文别名: (E)-2-2((1,3-dihydroxy-2-methylpropan-2-ylimino)methyl)phenol；(E)-2-((1,3-dihydroxy-2-methylpropan-2-ylimino)methyl)phenol；2-((E)-(1,3-dihydroxy-2-methylpropan-2-ylimino)methyl)phenol；H3DHMP
• CAS: 1164273-65-7
• 化学式: C₁₁H₁₅NO₃
• 分子量: 209.245
• InChiKey: CHBRCMBNFDMGKE-WUXMJOGZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.55
• 重原子数：
  15.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  73.05
• 氢给体数：
  3.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  nickel(II) nitrate hexahydrate 、 2-{[(1E)-(2-hydroxyphenyl)methylene]amino}-2-methylpropane-1,3-diol 、 乙腈 以 甲醇 、 乙腈 为溶剂， 以91%的产率得到[Ni(II)(2-((E)-(1,3-dihydroxy-2-methylpropan-2-ylimino)methyl)phenolate(1-))2]*(acetonitrile)
  参考文献：
  名称：

  The interplay of O–H⋯O hydrogen bonding in the generation of three new supramolecular complexes of CuII, NiII and CoIII: Syntheses, characterization and structural aspects

  摘要：

  Three new coordination complexes, [Cu(L-1)(H2O)] (1), [Ni(L-2)(2)]center dot CH3CN (2) and [Co(HL3)(L-3)] (3) [where H2L1, N,N'-bis(3-methoxysalicylidenimino)-1,3-diamino-propane; HL2, 2-((E)-(1,3-dihydroxy-2-methyl-propan-2-ylimino)methyl)phenol; H2L3, 2-((E)-(2-hydroxyethylimino)methyl)-4-bromophenol] have been synthesized and systematically characterized by elemental analyses, FT-IR, electronic spectroscopy, cyclic voltammetry and thermogravimetric analyses. Single crystal X-ray diffraction studies confirm that the metal center in complex 1 has distorted square-pyramidal geometry while it is distorted octahedral in the other two complexes. In all the complexes O-H center dot center dot center dot O hydrogen bondings assemble the molecular units leading to ordered supramolecular architectures. While both complexes 1 and 2 form infinite one-dimensional arrays through the self organisation of hydrogen bonded ring motifs, complex 3 is a unique star-shaped cyclic hexamer generated through intermolecular hydrogen bonding. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2009.01.002
• 作为产物：
  描述：

  水杨醛 、 2-氨基-2-甲基-1,3-丙二醇 以 甲醇 为溶剂， 反应 4.0h， 以94%的产率得到2-{[(1E)-(2-hydroxyphenyl)methylene]amino}-2-methylpropane-1,3-diol
  参考文献：
  名称：

  Cu（ii）-叠氮化物催化剂存在下绿色点击合成水中的β-羟基-1,2,3-三唑：Cu（ii）-叠氮化物配合物的新功能†

  摘要：

  一种新的Cu（II） -叠氮化物复合物，[铜（H 2 L）（N 3）]·CH 3 OH（1），是由铜（NO的反应合成3）2 3H 2 ö用2 - {[在叠氮化物阴离子和甲醇溶剂的存在下，（1 E）-（2-羟基苯基）亚甲基]氨基} -2-甲基丙烷-1，3-二醇（H 3 L）。通过元素分析和光谱法（FT-IR和UV-Vis）对络合物进行表征，并通过单晶X射线分析确定其结构。X射线研究表明，该化合物的不对称单元是Cu（II）通过端到端（EE）-叠氮化物桥转化为双核。络合物1被用作在绿色溶剂中的三组分叠氮化物-环氧化物-炔烃环加成反应的催化剂。研究了催化剂用量，温度以及叠氮化物对环加成反应的影响，并通过FT-IR，NMR和单晶X射线分析对产物进行了表征。在低于50°C的温度下，仅形成一种产物，而在更高的温度下，由于环氧化物的叠氮化物侵蚀而形成了两种化合物。结构研究表明，配合物1转化为四核Cu（II）配合物[Cu

  DOI：

  10.1039/c6nj03865d

文献信息

• Structure and magnetic property of a mixed-valence nonanuclear cobalt compound with a square-pyramidal CoII5 core
  作者：Zhong-Quan Jia、Xiao-Jun Sun、Li-Li Hu、Jun Tao、Rong-Bin Huang、Lan-Sun Zheng

  DOI：10.1039/b903733k

  日期：——

  A novel cobalt compound [Co9(HL)4(L)4Cl2]·(EtOH)2(H2O)2 (H3L = (E)-2-2((1,3-dihydroxy-2-methylpropan-2-ylimino)methyl) phenol) has been solvothermally synthesized and structurally characterized. The compound crystallised in the space groupC2/c with a = 32.624(2) Å, b = 9.4814(4) Å, c = 33.395(2) Å, β = 109.339(5)° and V = 9746.8(9) Å3. The crystal structure is a mixed-valence nonanuclear Co(II/III) oligomer, which contains a square-pyramidal CoII5 core formed through μ4-Cl and μ3-alkoxo bridges and the pentanuclear CoII5 core is surrounded by four peripheral Co(III) ions at the square-pyramidal base plane through μ2-alkoxo bridges. Magnetic properties of the compound can be considered as the magnetism of the CoII5 core, and the superexchange interactions between Co(II) ions within the core were calculated with three Co(II)–Co(II) superexchange parameters by using MAGPACK software package to give J1 = + 11.1 cm−1, J2 = −6.50 cm−1, J3 = −3.25 cm−1, D = + 6.0 cm−1 and g = 2.30.

  一种新型钴化合物[Co9(HL)4(L)4Cl2]·(EtOH)2(H2O)2 (H3L = (E)-2-2((1,3-二羟基-2-甲基丙-2-基亚氨基))甲基）苯酚）已通过溶剂热合成并进行了结构表征。该化合物在空间群C2/c中结晶，a = 32.624(2) Å，b = 9.4814(4) Å，c = 33.395(2) Å，β = 109.339(5)°，V = 9746.8(9) Å3。该晶体结构为混合价非核Co(II/III)低聚物，其包含通过μ4-Cl和μ3-烷氧基桥形成的方锥体CoII5核，五核CoII5核被四个外围Co(III)离子包围通过μ2-烷氧基桥在方锥体底面上。化合物的磁性可以被认为是CoII5核的磁性，利用MAGPACK软件包，用三个Co(II)–Co(II)超交换参数计算了核内Co(II)离子之间的超交换相互作用，给出 J1 = + 11.1 cm−1、J2 = −6.50 cm−1、J3 = −3.25 cm−1、D = + 6.0 cm−1 且 g = 2.30。
• Synthesis and magnetic properties of a new hexanuclear iron(III) compound
  作者：Guo-Min Wang、Rong-Jia Wei、Li-Li Hu、Xiao-Jun Sun、Rong-Bin Huang、Lan-Sun Zheng、Jun Tao

  DOI：10.1016/j.inoche.2009.05.005

  日期：2009.7

  NNSF of China [20671079, 20721001]; Key Project of Chinese Ministry of Education [107068]; 973 project [2007CB815301]; [NCET-08-0470]

  中国国家自然科学基金[20671079、20721001]；教育部重点项目[107068]；973项目[2007CB815301]；[NCET-08-0470]
• PROCESS FOR PREPARATION OF AMINO ALCOHOLS
  申请人：BASF SE

  公开号：US20210155575A1

  公开（公告）日：2021-05-27

  A process for the preparation of amino alcohols includes condensing a compound of Formula (II), a stereoisomer, a tautomer, or a salt thereof with a compound of Formula (IIIa) or Formula (IIIb), a stereoisomer, a tautomer, or a salt thereof to form a condensation product; hydroxylating or acyloxylating the condensation product in the presence of an oxidant to obtain a hydroxylation or acyloxylation product; and subjecting the hydroxylation or acyloxylation product to one or more subsequent reactions comprising a hydrolysis reaction, alcohol deprotection, an amino lysis reaction, or a combination of two or more thereof to obtain an amino alcohol of Formula (I).