2,5-Bis-o-(3-aminopropyl)-1,4:3,6-dianhydrohexitol | 6338-35-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃类
• 英文名称: 2,5-Bis-o-(3-aminopropyl)-1,4:3,6-dianhydrohexitol
• 英文别名: 3-[[6-(3-aminopropoxy)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl]oxy]propan-1-amine
• CAS: 6338-35-8
• 化学式: C₁₂H₂₄N₂O₄
• 分子量: 260.33
• InChiKey: XFDLDISETPZLMX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  18
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  89
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• NOVEL FUNCTIONAL COMPOUNDS WITH AN ISOSORBIDE OR ISOSORBIDE ISOMER CORE, PRODUCTION PROCESS AND USES OF THESE COMPOUNDS
  申请人：Gillet Jean-Philippe

  公开号：US20100130759A1

  公开（公告）日：2010-05-27

  The present invention relates to compounds of formula (I): R—(CH 2 ) 2 —O-A-O—(CH 2 ) 2 —R, in which A represents a divalent radical chosen from: and R represents —CN or —CH 2 NH 2 . In order to prepare them, acrylonitrile is reacted, via a Michael reaction, with a compound of formula (II): HO-A-OH, in which A is as defined above, in order to obtain a compound of formula (I) in which R represents —CN, and that the hydrogenation of the latter is carried out in order to obtain the corresponding compound of formula (I) in which R represents —CH 2 NH 2 . Use is made of a compound of formula (I) in which R represents —CH 2 NH 2 as a polar head in a surfactant, or as a monomer for a condensation polymerization, in particular in the manufacture of polyamides, or else as a crosslinking agents.

  本发明涉及公式（I）的化合物：R-（CH2）2-O-A-O-（ ）2-R，其中A代表从以下选择的双价基团：[图]，R代表-CN或- NH2。为了制备它们，通过Michael反应，用公式（II）的化合物反应HO-A-OH，其中A如上所定义，以获得公式（I）的化合物，其中R代表-CN，并对后者进行氢化，以获得相应的公式（I）的化合物，其中R代表- NH2。使用R代表- NH2的公式（I）的化合物作为表面活性剂中的极性头，或作为缩聚聚合物的单体，特别是在聚酰胺的制造中，或作为交联剂。
• DIISOCYANATE COMPOUND HAVING ANHYDROSUGAR ALCOHOL CORE AND PREPARATION METHOD THEREFOR
  申请人：Samyang Corporation

  公开号：EP3835302A1

  公开（公告）日：2021-06-16

  The present invention relates to a diisocynate compound having anhydrosugar alcohol core and a preparation method therefor and, more specifically, to a diisocynate compound having anhydrosugar alcohol core and a preparation method therefor, wherein the diisocynate compound is prepared through a reaction with a nitrile compound, a hydrogenation reaction, and an end-group substitution reaction while a recyclable, plant-based anhydrosugar alcohol or anhydrosugar alcohol-alkylene glycol is used as a raw material, and the diisocynate compound can be utilized in various fields, such as soft or hard polyurethane expanded foams, molded foams, coating, adhesives or glues, fibers, and polymer synthesis.

  本发明涉及一种以无水糖醇为核心的二异氰酸酯化合物及其制备方法，更具体地说，涉及一种以无水糖醇为核心的二异氰酸酯化合物及其制备方法，其中，二异氰酸酯化合物是通过与腈化合物反应、氢化反应和端基取代反应制备的，而以可回收的植物性无水糖醇或无水糖醇-烯二醇为原料，二异氰酸酯化合物可通过与腈化合物反应、氢化反应和端基取代反应制备、其中，二异炔酸盐化合物是通过与腈化合物反应、氢化反应和端基取代反应制备的，同时使用可回收的植物性无水糖醇或无水糖醇-烯二醇作为原料，该二异炔酸盐化合物可用于各种领域，如软质或硬质聚氨酯发泡、模塑泡沫、涂料、粘合剂或胶水、纤维和聚合物合成。
• NOUVEAUX COMPOSES FONCTIONNELS A COEUR D'ISOSORBIDE OU D'ISOMERE D'ISOSORBIDE, PROCEDE DE FABRICATION ET APPLICATIONS DE CES COMPOSES
  申请人：ARKEMA FRANCE

  公开号：EP2139900A2

  公开（公告）日：2010-01-06
• [EN] NOVEL FUNCTIONAL COMPOUNDS WITH AN ISOSORBIDE OR ISOSORBIDE ISOMER CORE, PRODUCTION PROCESS AND USES OF THESE COMPOUNDS<br/>[FR] NOUVEAUX COMPOSES FONCTIONNELS A COEUR D'ISOSORBIDE OU D'ISOMERE D'ISOSORBIDE, PROCEDE DE FABRICATION ET APPLICATIONS DE CES COMPOSES
  申请人：ARKEMA FRANCE

  公开号：WO2008145921A2

  公开（公告）日：2008-12-04

  [EN] The present invention relates to compounds of formula (I): R- (CH2)2-O-A-O-(CH2)2-R, in which A is a divalent radical selected from: (I), (II) and (III), and R is -CN or -CH2NH2. In order to prepare said compounds, acrylonitrile is brought to react, by means of a Michaelis reaction, with a compound of formula (II): HO-A-OH, in which A is as defined above, so as to obtain a compound of formula (I) in which R is -CN, and the latter is hydrogenated so as to obtain the corresponding compound of formula (I) in which R is -CH2NH2. A compound of formula (I) in which R is -CH2NH2 is used as a polar head in a surfactant, or as a monomer of a condensation polymerization, in particular in the production of polyamides, or else as a crosslinking agent.
  [FR] La présente invention porte sur des composés de formule (I) : R- (CH2) 2-O-A-O- (CH2) 2-R, dans laquelle A représente un radical divalent choisi parmi : (A), (B), (C), et R représente -CN ou -CH2NH2. Pour les préparer, on amène à réagir, par réaction de Michael, de l'acrylonitrile sur un composé de formule (II) : HO-A-OH, dans laquelle A est tel que défini ci-dessus, pour obtenir un composé de formule (I) dans laquelle R représente -CN, et que l'on réalise l'hydrogénation de ce dernier pour obtenir le composé correspondant de formule (I) dans laquelle R représente -CH2NH2. On utilise un composé de formule (I) dans laquelle R représente -CH2NH2 comme tête polaire dans un tensio-actif, ou comme monomère d'une polymérisation par condensation, en particulier dans la fabrication de polyamides, ou encore comme agent réticulant.
• [EN] DIISOCYANATE COMPOUND HAVING ANHYDROSUGAR ALCOHOL CORE AND PREPARATION METHOD THEREFOR<br/>[FR] COMPOSÉ DIISOCYANATE AYANT UN NOYAU D'ALCOOL D'ANHYDROSUCRE ET SON PROCÉDÉ DE PRÉPARATION<br/>[KO] 무수당 알코올 핵을 갖는 디이소시아네이트 화합물 및 이의 제조 방법
  申请人：SAMYANG CORP

  公开号：WO2020032611A1

  公开（公告）日：2020-02-13

  본 발명은 무수당 알코올 핵을 갖는 디이소시아네이트 화합물 및 이들의 제조 방법에 관한 것으로, 더욱 상세하게는, 재생 가능한 식물 기반의 무수당 알코올 또는 무수당 알코올-알킬렌 글리콜을 원료로 하여 니트릴 화합물과의 반응, 수소 첨가 반응 및 말단기 치환 반응을 통해 제조되며, 연질 또는 경질의 폴리우레탄 발포폼, 몰드폼, 코팅, 점착제 또는 접착제, 섬유, 고분자 합성 등의 다양한 분야에 활용될 수 있는, 무수당 알코올 핵을 갖는 디이소시아네이트 화합물 및 이의 제조 방법에 관한 것이다.