[tris(diethylamino)](diallylamino)phosphonium chloride | 1140972-92-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: [tris(diethylamino)](diallylamino)phosphonium chloride
• 英文别名: tris(diethylamino)diallylaminophosphonium chloride
• CAS: 1140972-92-4
• 化学式: C₁₈H₄₀N₄P*Cl
• 分子量: 378.969
• InChiKey: ZFQHWUFUCDOEOM-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.37
• 重原子数：
  24.0
• 可旋转键数：
  14.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  12.96
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  [tris(diethylamino)](diallylamino)phosphonium chloride 在 氟硼酸钠 作用下， 以 水 为溶剂， 反应 24.0h， 以70.1%的产率得到[tris(diethylamino)](diallylamino)phosphonium tetrafluoroborate
  参考文献：
  名称：

  Polysulfones of new structural types as perspective antioxidant agents

  摘要：

  A series of polysulfones of new structural types on the basis of azanorbornenes, 2,2-diallyl-1,1,3,3-tetraethylguanidiniumchloride and tris(diethylamino)diallylaminophosphonium salts were obtained by free radical polymerization reaction. Their antioxidant properties in lipid peroxidation induced by iron/ascorbate and in erythrocyte hemolysis by H2O2 were evaluated. The polysulfone of 2,2-diallyl-1,1,3,3-tetraethylguanidinium chloride showed protection of erythrocytes against hydrogen peroxide and thermal shock, protected epithelial cells against UV irradiation, was not toxic for erythrocytes, epithelial cells SPEV and 3T3 fibroblasts. The polysulfone of N-benzyl-2-azanorbornene-5 inhibited lipid peroxidation in liver homogenate, did not exhibit cytotoxicity in SPEV and 3T3 cells, protected these against UV irradiation. Both compounds had low bioavailability and may be recommended for further investigations as excipients to be externally applied. (c) 2013 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2013.03.007
• 作为产物：
  描述：

  [tris(diethylamino)](diallylamino)phosphazohydride 在 3-氯丙烯 、 sodium hydroxide 作用下， 以 水 为溶剂， 以86.5%的产率得到[tris(diethylamino)](diallylamino)phosphonium chloride
  参考文献：
  名称：

  Diallylaminophosphonium salts in radical polymerization reactions

  摘要：

  The activity of tris(diethylamino)diallylaminophosphonium tetrafluoroborate and chloride in radical polymerization reactions was studied. The kinetic relationships of the copolymerization with sulfur dioxide were examined.

  DOI：

  10.1134/s1070427208050224