(7α,17β)-15-Ethyl-17-hydroxy-7-methylestra-4,14-dien-3-one | 436143-47-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (7α,17β)-15-Ethyl-17-hydroxy-7-methylestra-4,14-dien-3-one
• 英文别名: (7R,8R,9R,10R,13S,17S)-15-ethyl-17-hydroxy-7,13-dimethyl-2,6,7,8,9,10,11,12,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one
• CAS: 436143-47-4
• 化学式: C₂₁H₃₀O₂
• 分子量: 314.468
• InChiKey: LMCXUCQAMVMYNW-UXTXICQDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  23
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.76
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• 14(15)-unsaturated 15- and/or 16-substituted androgens with mixed androgen-progrestational profile
  申请人：——

  公开号：US20040059140A1

  公开（公告）日：2004-03-25

  Disclosed are androgen-related steroids having a &Dgr;14 double bond and carrying a substituent at either or both of the carbon atoms nos. 15 and 16. The present steroids are characterized by possessing a mixed profile of androgenic and progestagenic activities. This makes these compounds suitable for male or female hormone replacement therapy, as well as male contraception.

  本发明涉及具有&Dgr;14双键并在碳原子15和16号中的一个或两个上携带取代基的雄激素相关类固醇。这些类固醇的特点是具有雄激素和孕激素活性的混合剖面。这使得这些化合物适用于男性或女性激素替代疗法，以及男性避孕。
• A process for forming a finish surface on a composite material
  申请人：BATTELLE MEMORIAL INSTITUTE

  公开号：EP0848025A2

  公开（公告）日：1998-06-17

  Thermally-reversible polymer compositions are obtained by reacting compounds with isocyanate and labile-hydrogen functionality. Aromatic polyimide, aromatic polycarbonate, polyarylsulfide, aromatic polyester with liquid crystal property, and polyarylimidazolidine oligomers are incorporated into the isocyanate or labile hydrogen compounds to give high-performance characteristics. Such thermally-reversible isocyanate-based polymer compositions with high-performance characteristics are useful, among other things, as finish surface coatings on composite materials such as polypropylene and polyethylene terephthalate. Novel phenolic-hydroxyl terminated polyarylsulfide and polyarylimidazolidine oligomers and their preparation are also described.

  通过对具有异氰酸酯和游离氢官能团的化合物进行反应，可获得热可逆聚合物组合物。芳香族聚酰亚胺、芳香族聚碳酸酯、聚芳基硫化物、具有液晶特性的芳香族聚酯和聚芳基咪唑烷低聚物被加入异氰酸酯或游离氢化合物中，以获得高性能特性。这种具有高性能特征的热可逆异氰酸酯基聚合物组合物，除其他外，可用作聚丙烯和聚对苯二甲酸乙二酯等复合材料的表面涂层。此外，还介绍了新型酚羟基端聚芳硫醚和聚芳基咪唑烷低聚物及其制备方法。
• THERMALLY-REVERSIBLE ISOCYANATE POLYMERS
  申请人：BATTELLE MEMORIAL INSTITUTE

  公开号：EP0514459B1

  公开（公告）日：2004-04-14
• THERMALLY REVERSIBLE ISOCYANATE-BASED POLYMERS
  申请人：BATTELLE MEMORIAL INSTITUTE

  公开号：EP0598039A1

  公开（公告）日：1994-05-25
• US5097010A
  申请人：——

  公开号：US5097010A

  公开（公告）日：1992-03-17