7-acetoxy-2-methyl-4-methoxy-1H-benzo[g]quinoline-2,5,10-trione | 479682-28-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 7-acetoxy-2-methyl-4-methoxy-1H-benzo[g]quinoline-2,5,10-trione
• 英文别名: (4-Methoxy-1-methyl-2,5,10-trioxobenzo[g]quinolin-7-yl) acetate
• CAS: 479682-28-5
• 化学式: C₁₇H₁₃NO₆
• 分子量: 327.293
• InChiKey: KONQQOCNAXFSLX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  90
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  7-acetoxy-2-methyl-4-methoxy-1H-benzo[g]quinoline-2,5,10-trione 在 盐酸 作用下， 以 1,4-二氧六环 为溶剂， 反应 2.0h， 生成 7-Hydroxy-4-methoxy-1-methyl-1H-benzo[g]quinoline-2,5,10-trione
  参考文献：
  名称：

  A Synthesis of Oxygenated 1-Azaanthra- quinones via Diels-Alder Reaction of 2,4-Dioxygenated Quinoline-5,8-diones with 1-Methoxy-3-trimethylsilyloxy- 1,3-butadiene

  摘要：

  Diels-Alder reaction of 2,4-dioxygenated quinoline-5,8-diones (7a, b and 8) with 1-methoxy-3-trimethylsilyloxy-1,3-butadiene (11) proceeded in a regio- and stereoselctive manner to give 2,4,6,8-tetraoxygenated 1-azaanthraquinoes (12a, b and 18) in good to moderate yields, respectively. The results demonstrated that Diels-Alder reaction of the 2,4-dioxygenated quinolone-5,8-diones with the activated diene provides a useful method for synthesizing highly oxygenated 1-azaanthraquinones.

  DOI：

  10.3987/com-02-9502
• 作为产物：
  描述：

  4,5,8-trimethoxy-1-methyl-1H-quinolin-2-one 在 ammonium cerium(IV) nitrate 、 silica gel 作用下， 以 水 、 甲苯 、 乙腈 、 苯 为溶剂， 反应 20.75h， 生成 7-acetoxy-2-methyl-4-methoxy-1H-benzo[g]quinoline-2,5,10-trione
  参考文献：
  名称：

  A Synthesis of Oxygenated 1-Azaanthra- quinones via Diels-Alder Reaction of 2,4-Dioxygenated Quinoline-5,8-diones with 1-Methoxy-3-trimethylsilyloxy- 1,3-butadiene

  摘要：

  Diels-Alder reaction of 2,4-dioxygenated quinoline-5,8-diones (7a, b and 8) with 1-methoxy-3-trimethylsilyloxy-1,3-butadiene (11) proceeded in a regio- and stereoselctive manner to give 2,4,6,8-tetraoxygenated 1-azaanthraquinoes (12a, b and 18) in good to moderate yields, respectively. The results demonstrated that Diels-Alder reaction of the 2,4-dioxygenated quinolone-5,8-diones with the activated diene provides a useful method for synthesizing highly oxygenated 1-azaanthraquinones.

  DOI：

  10.3987/com-02-9502