cyclomacroside C | 1152089-53-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: cyclomacroside C
• 英文别名: 3-O-α-L-rhamnopyranoside-24R-cycloartan-1α,3β,7β,24,25-pentaol；(2R,3R,4R,5R,6S)-2-[[(1S,3S,4S,6S,8S,10S,11S,12S,15R,16R)-15-[(2R,5R)-5,6-dihydroxy-6-methylheptan-2-yl]-4,10-dihydroxy-7,7,12,16-tetramethyl-6-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]-6-methyloxane-3,4,5-triol
• CAS: 1152089-53-6
• 化学式: C₃₆H₆₂O₉
• 分子量: 638.883
• InChiKey: ODTTULMJKJGJMN-RMUBQUPQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  45
• 可旋转键数：
  7
• 环数：
  6.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  160
• 氢给体数：
  7
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  cyclomacroside D 在 lyophilized dried gastric juice of grapevine snail (Helix pomatia) 作用下， 以 水 、 苯 为溶剂， 反应 730.5h， 以18 mg的产率得到cyclomacroside C
  参考文献：
  名称：

  Triterpene glycosides from Astragalus and their genins. LXXX. Cyclomacroside D, a new bisdesmoside

  摘要：

  从黄芪（豆科植物）中分离出了新的环木菠萝甙环木菠萝甙 D，其结构为 24R-cycloartan-1α,3β,7β,24,25-pentaol 3-O-α-L-鼠李糖苷-24-O-β-D-xylopyranoside。

  DOI：

  10.1007/s10600-009-9256-7

文献信息

• Triterpene glycosides from Astragalus and their genins. LXXXV. Structure of cyclomacroside E
  作者：D. A. Iskenderov、I. M. Isaev、M. I. Isaev

  DOI：10.1007/s10600-010-9580-y

  日期：2010.5

  The structure of a new cycloartane-type triterpene glycoside, cyclomacroside E, which was isolated from roots of Astragalus macropus Bunge (Leguminosae), was established as 3-O-α-L-rhamnopyranoside,24-O[(β-D-xylopyranosyl)(1→2)-β-D-xylopyranoside]-24R-cycloartan-1α,3β,7β,24,25-pentaol.

  从黄芪（豆科植物）根中分离出一种新的环木菠萝烷类三萜苷环木菠萝苷 E，其结构被确定为 3-O-α-L-rhamnopyranoside,24-O[(β-D-xylopyranosyl)(1→2)-β-D-xylopyranoside]-24R-cycloartan-1α,3β,7β,24,25-pentaol 。
• Triterpene glycosides from Astragalus and their genins. LXXX. Cyclomacroside D, a new bisdesmoside
  作者：D. A. Iskenderov、I. M. Isaev、M. I. Isaev

  DOI：10.1007/s10600-009-9256-7

  日期：2009.1

  The structure of the new cycloartane glycoside cyclomacroside D, which was isolated from Astragalus macropus Bunge (Leguminosae) and is 24R-cycloartan-1α,3β,7β,24,25-pentaol 3-O-α-L-rhamnopyranoside–24-O-β-D-xylopyranoside, was proved.

  从黄芪（豆科植物）中分离出了新的环木菠萝甙环木菠萝甙 D，其结构为 24R-cycloartan-1α,3β,7β,24,25-pentaol 3-O-α-L-鼠李糖苷-24-O-β-D-xylopyranoside。