(5-(4-bromophenyl)-3-(naphthalen-1-yl)penta-1,4-diynyl)trimethylsilane | 1310872-78-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (5-(4-bromophenyl)-3-(naphthalen-1-yl)penta-1,4-diynyl)trimethylsilane
• 英文别名: [5-(4-Bromophenyl)-3-naphthalen-1-ylpenta-1,4-diynyl]-trimethylsilane
• CAS: 1310872-78-6
• 化学式: C₂₄H₂₁BrSi
• 分子量: 417.42
• InChiKey: QTFLBMJQWMHIMF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.62
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  (4-溴苯基)乙炔 、 1-(naphthalen-1-yl)-3-(trimethylsilyl)prop-2-yn-1-ol 在 copper(II) bis(trifluoromethanesulfonate) 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 0.08h， 以80%的产率得到(5-(4-bromophenyl)-3-(naphthalen-1-yl)penta-1,4-diynyl)trimethylsilane
  参考文献：
  名称：

  Atom-Economical Chemoselective Synthesis of 1,4-Diynes and Polysubstituted Furans/Pyrroles from Propargyl Alcohols and Terminal Alkynes

  摘要：

  Under different conditions, the reaction of propargyl alcohols and terminal alkynes leads to the selective formation of 1,4-diynes and polysubstituted furans/pyrroles. Water is the only byproduct in the selective synthesis of 1,4-diynes and pyrroles, and the strategy for the furan synthesis is of 100% atom economy.

  DOI：

  10.1021/ol201054z

文献信息

• Atom-Economical Chemoselective Synthesis of 1,4-Diynes and Polysubstituted Furans/Pyrroles from Propargyl Alcohols and Terminal Alkynes
  作者：Tao Wang、Xin-liang Chen、Li Chen、Zhuang-ping Zhan

  DOI：10.1021/ol201054z

  日期：2011.7.1

  Under different conditions, the reaction of propargyl alcohols and terminal alkynes leads to the selective formation of 1,4-diynes and polysubstituted furans/pyrroles. Water is the only byproduct in the selective synthesis of 1,4-diynes and pyrroles, and the strategy for the furan synthesis is of 100% atom economy.