5'-(((2-methylnaphthalen-1-yl)(phenyl)phosphaneyl)oxy)-[1,1':4',1''-terphenyl]-2'-ol | 1579997-07-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 5'-(((2-methylnaphthalen-1-yl)(phenyl)phosphaneyl)oxy)-[1,1':4',1''-terphenyl]-2'-ol
• CAS: 1579997-07-1
• 化学式: C₃₅H₂₇O₂P
• 分子量: 510.572
• InChiKey: SPWBBVJTBJBJJS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.61
• 重原子数：
  38.0
• 可旋转键数：
  6.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.03
• 拓扑面积：
  29.46
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  5'-(((2-methylnaphthalen-1-yl)(phenyl)phosphaneyl)oxy)-[1,1':4',1''-terphenyl]-2'-ol 在 sulfur 作用下， 生成
  参考文献：
  名称：

  Asymmetric Synthesis of P-Stereogenic Diarylphosphinites by Palladium-Catalyzed Enantioselective Addition of Diarylphosphines to Benzoquinones

  摘要：

  The reaction of phenyl(2,4,6-trimethylphenyl)phosphine with a substituted benzoquinone in the presence of a chiral phosphapalladacycle complex as a catalyst and triethylamine in chloroform at -45 degrees C proceeded in a new type of addition manner to give a high yield of a 4-hydroxyphenyl phenyl(2,4,6-trimethylphenyl)phosphinite with 98% enantioselectivity, which is a versatile intermediate readily convertible into various phosphines and their derivatives with high enantiomeric purity.

  DOI：

  10.1021/ja501007t
• 作为产物：
  描述：

  magnesium,2-methyl-1H-naphthalen-1-ide,bromide 在 palladium diacetate 作用下， 以 四氢呋喃 、 氯仿 为溶剂， 反应 8.0h， 生成 5'-(((2-methylnaphthalen-1-yl)(phenyl)phosphaneyl)oxy)-[1,1':4',1''-terphenyl]-2'-ol
  参考文献：
  名称：

  Asymmetric Synthesis of P-Stereogenic Diarylphosphinites by Palladium-Catalyzed Enantioselective Addition of Diarylphosphines to Benzoquinones

  摘要：

  The reaction of phenyl(2,4,6-trimethylphenyl)phosphine with a substituted benzoquinone in the presence of a chiral phosphapalladacycle complex as a catalyst and triethylamine in chloroform at -45 degrees C proceeded in a new type of addition manner to give a high yield of a 4-hydroxyphenyl phenyl(2,4,6-trimethylphenyl)phosphinite with 98% enantioselectivity, which is a versatile intermediate readily convertible into various phosphines and their derivatives with high enantiomeric purity.

  DOI：

  10.1021/ja501007t