3-(4,4-difluoro-3,3-dimethyl-2-oxide-3,4-dihydroisoquinolin-1-yl)quinoline | 861648-62-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶并嘧啶类
• 英文名称: 3-(4,4-difluoro-3,3-dimethyl-2-oxide-3,4-dihydroisoquinolin-1-yl)quinoline
• 英文别名: 3-(4,4-difluoro-3,3-dimethyl-2-oxido-3,4-dihydroisoquinolin-1-yl)quinoline；4,4-Difluoro-3,3-dimethyl-2-oxido-1-quinolin-3-ylisoquinolin-2-ium
• CAS: 861648-62-6
• 化学式: C₂₀H₁₆F₂N₂O
• 分子量: 338.357
• InChiKey: NPAFZJCEPQNZHI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  25
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  41.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound
  申请人：Ito Hiroyuki

  公开号：US20080275242A1

  公开（公告）日：2008-11-06

  The invention provides compounds which exert excellent fungicidal activities against various plant diseases and are useful as active ingredients of pesticides permitting the control of rice blast and so on even in low dosages. Compounds represented by the general formulae (1a) to (1d) or salts thereof: (1a) (1b) (1c) (or) (1d) wherein R 1 and R 2 are each C 1-6 alkyl or the like; R 3 and R 4 are each hydrogen, halogeno, or the like; R 5 is hydrogen, C 1-6 alkyl, or the like; X is halogeno, C 1-6 alkyl, or the like; Y is halogeno, C 1-6 alkyl, or the like; n is an integer of 0 to 4; and m is an integer of 0 to 6.

  本发明提供了化合物，对各种植物病害具有优异的杀菌活性，可用作农药的活性成分，即使在低剂量下也可控制稻瘟病等。化合物由一般式（1a）至（1d）或其盐表示：（1a）（1b）（1c）（或）（1d），其中R1和R2均为C1-6烷基或类似物；R3和R4均为氢，卤素或类似物；R5为氢，C1-6烷基或类似物；X为卤素，C1-6烷基或类似物；Y为卤素，C1-6烷基或类似物；n为0至4的整数；m为0至6的整数。
• SOIL- OR SEED-TREATING AGENT COMPRISING QUINOLINE COMPOUND OR SALT THEREOF AS ACTIVE INGREDIENT, OR METHOD FOR CONTROL OF PLANT DISEASE USING THE SAME
  申请人：Sankyo Agro Company, Limited

  公开号：EP2103214A1

  公开（公告）日：2009-09-23

  A soil treating agent or a seed treating agent having excellent prevention effects against various plant pathogens (particularly against rice blast) is provided. A soil treating agent or seed treating agent, comprising one or more compounds of the general formula (Ia), (Ib) or (Ic): (wherein R1, R2: C1-C6 alkyl (may be substituted), aryl (may be substituted), heteroaryl (may be substituted), aralkyl (may be substituted) and the like; R3, R4: H, C1-C6 alkyl (may be substituted), halogen, C1-C6 alkoxy and the like; X: halogen, C1-C6 alkyl (may be substituted), C2-C6 alkenyl (may be substituted), C2-C6 alkynyl (may be substituted), aryl (may be substituted), heteroaryl (may be substituted), C1-C6 alkoxy and the like; Y: halogen, C1-C6 alkyl, C1-C6 alkoxy, OH; n: 0 to 4; m: 0 to 6) or salts thereof as an active ingredient.

  本发明提供了一种土壤处理剂或种子处理剂，对各种植物病原体（尤其是稻瘟病）具有极佳的预防效果。一种土壤处理剂或种子处理剂，包含一种或多种通式（Ia）、（Ib）或（Ic）的化合物： (其中 R1、R2：C1-C6烷基（可被取代）、芳基（可被取代）、杂芳基（可被取代）、芳烷基（可被取代）等；R3、R4：H、C1-C6烷基（可被取代）、卤素、C1-C6烷氧基等；X：卤素、C1-C6 烷基（可被取代）、C2-C6 烯基（可被取代）、C2-C6 炔基（可被取代）、芳基（可被取代）、杂芳基（可被取代）、C1-C6 烷氧基等；Y：卤素、C1-C6 烷基、C1-C6 烷氧基、OH；n：0 至 4；m：0 至 6）。 或其盐类作为活性成分。
• 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES
  申请人：MITSUI CHEMICALS AGRO, INC.

  公开号：EP1736471B1

  公开（公告）日：2014-01-08
• USE OF QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENTS IN SOIL- OR SEED-TREATING AGENTS AND METHOD FOR CONTROL OF PLANT DISEASE
  申请人：Mitsui Chemicals Agro, Inc.

  公开号：EP2103214B1

  公开（公告）日：2013-10-23
• SOIL TREATING AGENT OR SEED TREATING AGENT COMPRISING QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENT,OR METHOD FOR PREVENTING PLANT DISEASES BY USING THE SAME
  申请人：Ito Hiroyuki

  公开号：US20090325998A1

  公开（公告）日：2009-12-31

  A soil treating agent or a seed treating agent having excellent prevention effects against various plant pathogens (particularly against rice blast) is provided. A soil treating agent or seed treating agent, comprising one or more compounds of the general formula (Ia), (Ib) or (Ic): (wherein R 1 , R 2 : C 1 -C 6 alkyl (may be substituted), aryl (may be substituted), heteroaryl (may be substituted), aralkyl (may be substituted) and the like; R 3 , R 4 : H, C 1 -C 6 alkyl (may be substituted), halogen, C 1 -C 6 alkoxy and the like; X: halogen, C 1 -C 6 alkyl (may be substituted), C 2 -C 6 alkenyl (may be substituted), C 2 -C 6 alkynyl (may be substituted), aryl (may be substituted), heteroaryl (may be substituted), C 1 -C 6 alkoxy and the like; Y: halogen, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, OH; n: 0 to 4; m: 0 to 6) or salts thereof as an active ingredient.