23,24-Dinor-cholen-(7)-3β,5α-diol-6-on-22-saeure-3-acetat | 7703-77-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 23,24-Dinor-cholen-(7)-3β,5α-diol-6-on-22-saeure-3-acetat
• 英文别名: 20S-3β-Acetoxy-5α-hydroxy-6-oxo-5α-pregnen-7-20-carbonsaeure
• CAS: 7703-77-7
• 化学式: C₂₄H₃₄O₆
• 分子量: 418.53
• InChiKey: SDMUEUOOIAJXJG-CCLZQIBBSA-N

反应信息

• 作为反应物：
  描述：

  23,24-Dinor-cholen-(7)-3β,5α-diol-6-on-22-saeure-3-acetat 在 溶剂黄146 、 锌 作用下， 生成 (20S)-3β-Acetoxy-6-oxo-5α-pregnen-(7)-20-carbonsaeure
  参考文献：
  名称：

  Zur Synthese des Ecdysons. III. Mitteilung über Insektenhormone. Synthesen von 2β, 3β, 14α-Trihydroxy-6-keto-Δ⁷-A|B-cis-Steroiden

  摘要：

  AbstractThe synthesis of the tetracyclic skeleton of ecdysone with correct stereochemistry and substitution is described. 22,25‐Didehydroxy‐ecdysone and methyl (20S)‐2β,3β‐dihydroxy‐6‐oxo‐5β‐pregn‐7‐ene‐20‐carboxylate have been prepared. The latter is a key intermediate in the synthesis of ecdysone.

  DOI：

  10.1002/hlca.19660490518
• 作为产物：
  描述：

  Acetic acid (3S,5R,9S,10R,13R,14R,17R)-5-hydroxy-10,13-dimethyl-17-((R)-1-methyl-allyl)-6-oxo-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 生成 23,24-Dinor-cholen-(7)-3β,5α-diol-6-on-22-saeure-3-acetat
  参考文献：
  名称：

  Zur Synthese des Ecdysons. III. Mitteilung über Insektenhormone. Synthesen von 2β, 3β, 14α-Trihydroxy-6-keto-Δ⁷-A|B-cis-Steroiden

  摘要：

  AbstractThe synthesis of the tetracyclic skeleton of ecdysone with correct stereochemistry and substitution is described. 22,25‐Didehydroxy‐ecdysone and methyl (20S)‐2β,3β‐dihydroxy‐6‐oxo‐5β‐pregn‐7‐ene‐20‐carboxylate have been prepared. The latter is a key intermediate in the synthesis of ecdysone.

  DOI：

  10.1002/hlca.19660490518