2-Chlor-9-<3-piperazino-propyliden>-thioxanthen | 21642-94-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻喃类
• 英文名称: 2-Chlor-9-<3-piperazino-propyliden>-thioxanthen
• 英文别名: 1-[3-(2-chloro-thioxanthen-9-ylidene)-propyl]-piperazine；1-[3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl]piperazine；1-[3-(2-chlorothioxanthen-9-ylidene)propyl]piperazine
• CAS: 21642-94-4
• 化学式: C₂₀H₂₁ClN₂S
• 分子量: 356.919
• InChiKey: SLTQOJGWYUTULB-UHFFFAOYSA-N

物化性质

• 沸点：
  520.2±50.0 °C(Predicted)
• 密度：
  1.271±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  40.6
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2934999090

文献信息

• Thioxanthene derivatives for use in the treatment of infectious diseases
  申请人：BKG Pharma ApS

  公开号：EP2301545A1

  公开（公告）日：2011-03-30

  The present invention is directed to certain thioxanthene derivatives and phenothiazine derivatives suitable for use as anti-infective agents, in particular, for treatment of infectious diseases. The invention furthermore relates to compositions comprising said anti-infective agents.

  本发明涉及某些适合用作抗感染剂，特别是用于治疗传染病的噻吨烷衍生物和吩噻嗪衍生物。本发明还涉及包含上述抗感染剂的组合物。
• THIOXANTHENE DERIVATES USEFULTO TREAT INFECTIOUS DISEASES
  申请人：BKG Pharma ApS

  公开号：EP2114406A1

  公开（公告）日：2009-11-11
• THIOXANTHENE DERIVATES AS SOLE ANTI-INFECTIVE AGENTS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES
  申请人：BKG Pharma ApS

  公开号：EP2114406B1

  公开（公告）日：2011-05-25
• THIOXANTHENE DERIVATES USEFUL TO TREAT INFECTIOUS DISEASES
  申请人：Giwercman Birgit Kjældgaard

  公开号：US20100113430A1

  公开（公告）日：2010-05-06

  The present invention is directed to certain thioxanthene derivatives and phenothiazine derivatives suitable for use as anti-infective agents, in particular, for treatment of infectious diseases. The invention furthermore relates to compositions comprising said anti-infective agents.
• [EN] THIOXANTHENE DERIVATES USEFULTO TREAT INFECTIOUS DISEASES<br/>[FR] DÉRIVÉS DE THIOXANTHÈNE UTILES POUR TRAITER LES MALADIES INFECTIEUSES
  申请人：BKG PHARMA APS

  公开号：WO2008080408A1

  公开（公告）日：2008-07-10

  [EN] The present invention is directed to certain thioxanthene derivatives and phenothiazine derivatives suitable for use as anti-infective agents, in particular, for treatment of infec- tious diseases. The invention furthermore relates to compositions comprising said anti- infective agents.
  [FR] La présente invention concerne certains dérivés de thioxanthène et certains dérivés de phénothiazine qui peuvent être utilisés en tant qu'agents anti-infectieux, notamment pour le traitement de maladies infectieuses. L'invention concerne également des compositions comprenant lesdits agents anti-infectieux.