[Pd(1,2,3,4-tetrahydroisoquinolinedithiocarbamate)(triphenylphosphine)Cl] | 1218949-02-0

• 英文名称: [Pd(1,2,3,4-tetrahydroisoquinolinedithiocarbamate)(triphenylphosphine)Cl]
• 英文别名: Pd(TIQDTC)(PPh3)Cl
• CAS: 1218949-02-0
• 化学式: C₂₈H₂₅ClNPPdS₂
• 分子量: 612.492
• InChiKey: QBAGJTGHCWTTHU-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  (ThiqDtc)H 、 bis-triphenylphosphine-palladium(II) chloride 以 二氯甲烷 为溶剂， 以85%的产率得到[Pd(1,2,3,4-tetrahydroisoquinolinedithiocarbamate)(triphenylphosphine)Cl]
  参考文献：
  名称：

  In vitro assessment of cytotoxicity, anti-inflammatory, antifungal properties and crystal structures of metallacyclic palladium(II) complexes

  摘要：

  Metallacyclic palladium(II) complexes [Pd(L)(R3P)Cl], L = TIQDTC (1,2,3,4-tetrahydroisoquinolinedithiocarbamate), 4MpipDTC (4-methylpipradinedithiocarbamate), MPizDTC (N-methylpiperazinedithiocarbamate), R3P = Ph3P, (o-tolyl)(3)P, Ph2ClP, were synthesized in a 1:1 molar metal-ligand ratio. These complexes were characterized by elemental analyses, FT-IR, multinuclear (H-1, C-13 and P-31) NMR. The X-ray crystal structures of [Pd(TIQDTC)(Ph3P)Cl] and [Pd(TIQDTC)((o-tolyl)(3)P)Cl] show a slightly distorted square planar environment around the Pd(II) ion with S-Pd-S and P-Pd-Cl average bond angles of 74.51 and 92.41, respectively. These complexes were screened for cytotoxic, antifungal, anti-inflammatory and antibacterial activity. Some complexes exhibit a significant activity against fungi. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2009.10.048