α-Benzyl-α-phenyl-4-pyridinmethanol | 94256-60-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: α-Benzyl-α-phenyl-4-pyridinmethanol
• 英文别名: 4-(1-hydroxy-1,2-diphenylethyl)pyridine；1,2-diphenyl-1-[4]pyridyl-ethanol；1,2-Diphenyl-1-[4]pyridyl-aethanol；1,2-diphenyl-1-pyridin-4-ylethanol
• CAS: 94256-60-7
• 化学式: C₁₉H₁₇NO
• 分子量: 275.35
• InChiKey: KAKCFWVMRWAVCR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  33.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  α-Benzyl-α-phenyl-4-pyridinmethanol 、 苯 在 三氟甲磺酸 作用下， 反应 2.0h， 以97%的产率得到4-(1,2,2-triphenylethyl)pyridine
  参考文献：
  名称：

  Charge Migration in Dicationic Electrophiles and Its Application to the Synthesis of Aza-polycyclic Aromatic Compounds

  摘要：

  Superacid-promoted reactions of dicationic electrophiles have been studied, and the positive charge centers are found to migrate apart in a predictable manner. Using isotopic labeling the charge migration is found in one system to occur through successive deprotonation-reprotonation steps. The charge migration chemistry is the basis for new general synthetic route to aza-polycyclic aromatic compounds.

  DOI：

  10.1021/ol060125u
• 作为产物：
  描述：

  4-苯甲酰吡啶 、 苄基氯化镁 在 乙醚 作用下， 生成 α-Benzyl-α-phenyl-4-pyridinmethanol
  参考文献：
  名称：

  Phosphoramides

  摘要：

  公开号：

  US02832786A1

文献信息

• Phosphoramides
  申请人：WM S MERRELL CO

  公开号：US02832786A1

  公开（公告）日：1958-04-29
• Charge Migration in Dicationic Electrophiles and Its Application to the Synthesis of Aza-polycyclic Aromatic Compounds
  作者：Ang Li、Patrick J. Kindelin、Douglas A. Klumpp

  DOI：10.1021/ol060125u

  日期：2006.3.1

  Superacid-promoted reactions of dicationic electrophiles have been studied, and the positive charge centers are found to migrate apart in a predictable manner. Using isotopic labeling the charge migration is found in one system to occur through successive deprotonation-reprotonation steps. The charge migration chemistry is the basis for new general synthetic route to aza-polycyclic aromatic compounds.