[1-(4-bromophenyl)sulfonyloxy-7-[(2E)-3,7-dimethylocta-2,6-dienoxy]-9-oxoxanthen-3-yl] 4-bromobenzenesulfonate | 1151549-74-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: [1-(4-bromophenyl)sulfonyloxy-7-[(2E)-3,7-dimethylocta-2,6-dienoxy]-9-oxoxanthen-3-yl] 4-bromobenzenesulfonate
• CAS: 1151549-74-4
• 化学式: C₃₅H₃₀Br₂O₉S₂
• 分子量: 818.558
• InChiKey: WBASIKGDFMCODI-HAVVHWLPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.9
• 重原子数：
  48
• 可旋转键数：
  12
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  139
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  7-geranyloxy-1,3-dihydroxyxanthone 、 4-溴苯磺酰氯 在 potassium carbonate 作用下， 以 二氯甲烷 为溶剂， 以75.2 mg的产率得到[1-(4-bromophenyl)sulfonyloxy-7-[(2E)-3,7-dimethylocta-2,6-dienoxy]-9-oxoxanthen-3-yl] 4-bromobenzenesulfonate
  参考文献：
  名称：

  Anti-Pseudomonas aeruginosa xanthones from the resin and green fruits of Cratoxylum cochinchinense

  摘要：

  Cochinchinones 1-L (1-3 and 13) along with 11 known xanthones (4-12,14, and 15) were isolated from the resin and green fruits of Cratoxylum cochinchinense. In addition, four new acetylated compounds (1619) were derivatized from 7-geranyloxy-1,3-dihydroxyxanthone (14) and 3-geranyloxy-1,7-dihydroxyxanthone (15). All compounds were characterized on the basis of spectroscopic analyses. The structures of cochinchinone I (1), a monoacetate (18) and a dibrosylate (20), were also confirmed by X-ray diffraction analysis. The antibacterial and antifungal activities of selected Compounds were evaluated as well. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.01.083