N,N-dimethyl-N-(2-(2-hydroxyethoxy)) ammonium propionate | 1294494-64-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-dimethyl-N-(2-(2-hydroxyethoxy)) ammonium propionate
• 英文别名: N,N-dimethyl-N-(2-hydroxyethoxyethyl)ammonium propionate；2-(2-hydroxyethoxy)ethyl-dimethylazanium;propanoate
• CAS: 1294494-64-6
• 化学式: C₃H₆O₂*C₆H₁₅NO₂
• 分子量: 207.27
• InChiKey: VMWSAPMBSQHTPI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.71
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  74
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  N,N-二甲基氨乙基乙二醇 、 丙酸 反应 24.5h， 生成 N,N-dimethyl-N-(2-(2-hydroxyethoxy)) ammonium propionate
  参考文献：
  名称：

  Extraction process of sulfur compounds from fuels with protic ionic liquids

  摘要：

  燃料中的硫化合物对环境有害，构成了一项巨大挑战。本研究设计了一系列质子离子液体（PILs），并评估了它们的萃取脱硫能力。

  DOI：

  10.1039/c4ra16186f

文献信息

• Microwave-assisted extraction of lactones from Ligusticum chuanxiong Hort. using protic ionic liquids
  作者：Chi Yansheng、Zhang Zhida、Li Changping、Liu Qingshan、Yan Peifang、Urs Welz-Biermann

  DOI：10.1039/c0gc00864h

  日期：——

  Traditional Chinese medicine is still the main source for medical treatment in China. Extraction processes are usually adopted to separate bioactive ingredients from local plants. However, volatile traditional organic solvents are commonly used in the extraction process, which would lead to solvent loss and environment pollution. In this work, in order to improve the extraction process and develop a greener process, a microwave-assisted extraction (MAE) method was investigated to extract senkyunolide I, senkyunolide H and Z-ligustilide from Ligusticum chuanxiong Hort. Two ionic liquids, N,N-dimethyl-N-(2-hydroxyethoxyethyl)ammonium propionate (DMHEEAP) and N,N-dimethyl(cyanoethyl)ammonium propionate (DMCEAP), were employed as extractants. Important factors such as system temperature, extraction time, solid-to-solvent ratio and particle size were studied. The results show the system temperature was main factor which affects the microwave assisted extraction process. The extraction equilibrium could be reached in a short period of time. The extraction efficiency was not affected by the phase ratio within a certain solid/solvent ratio range. The particle size of Ligusticum chuanxiong powder had no remarkable effect on extraction efficiency. The back-extraction of protic ionic liquids using n-hexane was realized, and the concentration of senkyunolide I and senkyunolide H hardly decreased, but the concentration of Z-ligustilide decreased by 39.7%. The extraction mechanism of the investigated microwave assisted ionic liquid extraction was the same as traditional organic solvent extraction.

  中药仍然是中国医疗的主要来源。从当地植物中分离生物活性成分通常采用萃取工艺。然而，萃取过程中通常使用挥发性传统有机溶剂，这将导致溶剂流失和环境污染。为了改进萃取工艺，开发绿色工艺，本研究采用微波辅助萃取法（MAE）从川芎中提取川芎内酯I、川芎内酯H和Z-藁本内酯。采用 N,N-二甲基-N-（2-羟乙基氧乙基）丙酸铵（DMHEEAP）和 N,N-二甲基（氰乙基）丙酸铵（DMCEAP）两种离子液体作为萃取剂。研究了体系温度、萃取时间、固溶比和粒度等重要因素。结果表明，系统温度是影响微波辅助萃取过程的主要因素。萃取平衡可在短时间内达到。在一定的固体/溶剂比例范围内，萃取效率不受相比例的影响。川芎粉末的粒度对萃取效率无明显影响。用正己烷对原生离子液体进行反萃取，川芎内酯I和川芎内酯H的浓度几乎没有下降，但Z-藁本内酯的浓度下降了39.7%。所研究的微波辅助离子液体萃取的萃取机理与传统的有机溶剂萃取相同。