3,7-二甲基壬-6-烯-1-炔-3-醇 | 79992-72-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 中文名称: 3,7-二甲基壬-6-烯-1-炔-3-醇
• 英文名称: Elsinore pill
• 英文别名: (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol;1,3,7-trimethylpurine-2,6-dione
• CAS: 79992-72-6
• 化学式: C18H25N5O3
• 分子量: 359.4
• InChiKey: CTSFIJCLRRGCGJ-GNAZCLTHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  90.7
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
  申请人：ELCELYX THERAPEUTICS, INC.

  公开号：US10159658B2

  公开（公告）日：2018-12-25

  Compositions and methods comprising at least one biguanide compound and at least one statin combined with at least one additional active agent in fixed dose combinations are provided for reducing cardiometabolic risk, and for the treatment of cardiovascular disease, wherein the biguanide compound is formulated for delayed release.

  本发明提供了包含至少一种双胍类化合物和至少一种他汀类药物以及至少一种额外活性剂的组合物和方法，其固定剂量组合物用于降低心脏代谢风险和治疗心血管疾病，其中双胍类化合物配制成缓释剂。
• COMPOSITIONS COMPRISING STATINS, BIGUANIDES AND FURTHER AGENTS FOR REDUCING CARDIOMETABOLIC RISK
  申请人：Elcelyx Therapeutics, Inc.

  公开号：EP2872127A1

  公开（公告）日：2015-05-20
• Compositions Comprising Statins, Biguanides and Further Agents for Reducing Cardiometabolic Risk
  申请人：Elcelyx Theraeutics, Inc.

  公开号：US20150196509A1

  公开（公告）日：2015-07-16

  Compositions and methods comprising at least one biguanide compound and at least one statin combined with at least one additional active agent in fixed dose combinations are provided for reducing cardiometabolic risk, and for the treatment of cardiovascular disease, wherein the biguanide compound is formulated for delayed release.
• US5422352A
  申请人：——

  公开号：US5422352A

  公开（公告）日：1995-06-06
• US9572784B2
  申请人：——

  公开号：US9572784B2

  公开（公告）日：2017-02-21