| 1064197-12-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1064197-12-1
• 化学式: C₃₆H₃₄F₆O₁₁
• 分子量: 756.65
• InChiKey: BWAGBNFWZUBLTP-VEMIDSOESA-N

反应信息

• 作为产物：
  描述：

  11(R)-hydroxymonocerin 、 甲氧基-三氟甲基苯 在 吡啶 、 4-二甲氨基吡啶 作用下， 生成
  参考文献：
  名称：

  11-Hydroxymonocerin from the Plant Endophytic Fungus Exserohilum rostratum

  摘要：

  A new analogue of monocerin, 11-hydroxymonocerin (2), along with monocerin (1) and 12-hydroxymonocerin (3) were isolated from Cultures of Exserohilum rostratum, a fungal strain endophytic in Stemona sp. The structure of 2 was determined by analysis of NMR and MS data and by comparison of spectroscopic data to those of 1. Monocerin (1) and 11-hydroxymonoccrin (2) displayed activity against Plasmodium falciparum (K 1, multidrug-resistant strain) with IC50 values of 0.68 and 7.70 mu M, respectively. None of the compounds were cytotoxic against any of the tumor cell lines tested.

  DOI：

  10.1021/np8004024