5β-Aetiansaeure-methylester | 88929-08-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 5β-Aetiansaeure-methylester
• 英文别名: Etiocholanic acid methyl ester；methyl (5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylate
• CAS: 88929-08-2
• 化学式: C₂₁H₃₄O₂
• 分子量: 318.5
• InChiKey: UYRKOPHGLDACOQ-WPWXJNKXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3,12-dioxo-5β-androstane-17β-carboxylic acid 在 盐酸 、 amalgamated zinc 、 乙醚 、 溶剂黄146 作用下， 生成 5β-Aetiansaeure-methylester
  参考文献：
  名称：

  Ein neuer Abbau des Digoxigenins

  摘要：

  DOI：

  10.1002/hlca.193802101108

文献信息

• �ber Bestandteile der Nebennierenrinde und verwandte Stoffe. 34. Mitteilung. Desoxy-corticosteron und andere Pregnanderivate aus �tio-lithochols�ure und 3 ?-Oxy-�tio-cholans�ure
  作者：T. Reichstein、H. G. Fuchs

  DOI：10.1002/hlca.19400230185

  日期：——
• Wieland; Schlichting; Jacobi, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1926, vol. 161, p. 80,102
  作者：Wieland、Schlichting、Jacobi

  DOI：——

  日期：——
• Desulphurization of the thioketal of testosterone acetate with deactivated raney nickel
  作者：V. Permutti、N. Danieli、Y. Mazur

  DOI：10.1016/s0040-4020(01)96337-9

  日期：1968.1
• Analysis of the intensification of tsunami waves near the South Coast of Crimea
  作者：S. F. Dotsenko

  DOI：10.1007/bf02519255

  日期：2000.11
• Can germplasm resources be used to increase the ascorbic acid content of stored potatoes?
  作者：Corinne S. Davies、Michael J. Ottman、Stanley J. Peloquin

  DOI：10.1007/bf02986362

  日期：2002.7

  Freshly harvested potato tubers contain up to 50 mg/100g ascorbic acid (AA), but levels decline rapidly during cold storage. Genetic alterations to boost the AA content of stored tubers would contribute to human nutrition and might improve tuber resistance to oxidative damage during chilling. While studying the breeding potential of Solanum phureja germplasm, we identified a 24-chromosome Phureja-haploid Tuberosum hybrid (clone I, USW5295.7) that retained a twofold higher content of tuber AA than neighboring clones after storage at 5 C. Clone I produces 2n-pollen through a mechanism genetically equivalent to first-division restitution (FDR), which transmits much of the nonadditive genetic variance for tuber yield. We now report a survey of clone I progeny showing significant family and ploidy effects on tuber AA levels during cold storage, consistent with the transmission of information for higher AA by FDR 2n-pollen. These results encourage further study of 2n-gametes and wild species germplasm to breed for increased tuber AA.