methyl 4-((1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)benzoate | 150127-62-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: methyl 4-((1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)benzoate
• 英文别名: 4-(1,4-dioxo-1,4-dihydro-[2]naphthylamino)-benzoic acid methyl ester；4-(1,4-Dioxo-1,4-dihydro-[2]naphthylamino)-benzoesaeure-methylester；2-(4-Carbomethoxy-anilino)-naphthochinon-(1.4)；Methyl 4-[(1,4-dioxonaphthalen-2-yl)amino]benzoate；methyl 4-[(1,4-dioxonaphthalen-2-yl)amino]benzoate
• CAS: 150127-62-1
• 化学式: C₁₈H₁₃NO₄
• 分子量: 307.306
• InChiKey: SIWHFHZPZBFAAX-UHFFFAOYSA-N

物化性质

• 沸点：
  485.9±45.0 °C(predicted)
• 密度：
  1.375±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为反应物：
  描述：

  methyl 4-((1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)benzoate 在 palladium diacetate 、 溶剂黄146 作用下， 以58 %的产率得到methyl 6,11-dioxo-6,11-dihydro-5H-benzo[b]carbazole-2-carboxylate
  参考文献：
  名称：

  BENZOCARBAZOLE DERIVATIVES AS INHIBITORS OF DRP1

  摘要：

  The present application relates to compounds of Formula (I), Formula (II), and Formula (III) and to pharmaceutically acceptable salts and solvates of any of the foregoing, as well as pharmaceutical compositions and methods of using same to treat various diseases such as neurological and cardiac disorders.

  公开号：

  WO2023249965A1
• 作为产物：
  描述：

  4-氨基苯甲酸甲酯 、 1,4-萘醌 在 cerium(III) chloride heptahydrate 作用下， 以 乙醇 为溶剂， 以37 %的产率得到methyl 4-((1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)benzoate
  参考文献：
  名称：

  BENZOCARBAZOLE DERIVATIVES AS INHIBITORS OF DRP1

  摘要：

  The present application relates to compounds of Formula (I), Formula (II), and Formula (III) and to pharmaceutically acceptable salts and solvates of any of the foregoing, as well as pharmaceutical compositions and methods of using same to treat various diseases such as neurological and cardiac disorders.

  公开号：

  WO2023249965A1