tetrabutylammonium pyruvate | 908338-86-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: tetrabutylammonium pyruvate
• 英文别名: 2-Oxopropanoate;tetrabutylazanium
• CAS: 908338-86-3
• 化学式: C₃H₃O₃*C₁₆H₃₆N
• 分子量: 329.524
• InChiKey: GXJYKPPJIACOQC-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  3.33
• 重原子数：
  23
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  57.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  tetrabutylammonium pyruvate 、 1-(9-butyl-9H-purin-6-yl)-3-(2-nitrophenyl)urea 以 氯仿 为溶剂， 生成
  参考文献：
  名称：

  Adenyl nitrourea in molecular recognition of fluoride and pyruvate

  摘要：

  腺苷衍生物 1 具有阴离子相互作用的特性。与之前报告的化合物 2 和 3 相比，化合物 1 在 CHCl3 中与碱性阴离子 F- 和丙酮酸发生了相互作用。荧光、紫外-可见光和 1H NMR 光谱方法说明了这种结合作用。理论研究解释了 1 在 CHCl3 中与 F- 和丙酮酸的构象行为和结合特征。

  DOI：

  10.1139/cjc-2022-0060
• 作为产物：
  描述：

  四丁基氢氧化铵 、 丙酮酸 以 水 为溶剂， 反应 24.0h， 以93%的产率得到tetrabutylammonium pyruvate
  参考文献：
  名称：

  Biomass derived ionic liquids: synthesis from natural organic acids, characterization, toxicity, biodegradation and use as solvents for catalytic hydrogenation processes

  摘要：

  Ionic liquids with natural organic derived anions (L-lactate, L-tartrate, malonate, succinate, L-malate, pyruvate, D-glucuronate, D-galacturonate) were easily prepared from tetrabutylammonium hydroxide and an excess of the corresponding acid with good yields. Their characterization was realized through classical NMR, IR, and elemental analysis techniques; their viscosity and TGA (thermogravimetric analysis) parameters were also determined. These ionic liquids showed good performance and recyclability in the selective catalytic hydrogenation of 1,5-cyclooctadiene (1,5-COD) into cyclooctene (COD) at room temperature under atmospheric H-2 pressure.Antimicrobial toxicity assays toward a large panel of bacteria and fungi strains were also completed and biodegradation studies (Closed Bottle test, 28 days) were also performed. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.05.054

文献信息

• Naphthyridine amide–urea conjugate: a case toward selective fluorometric sensing of N-acetyl proline carboxylate
  作者：Kumaresh Ghosh、Tanmay Sarkar

  DOI：10.1007/s10847-011-9929-2

  日期：2011.10

  A simple neutral naphthyridine-based chemosensor 1, which selectively recognizes the tetrabutylammonium salt of N-acetyl-l-proline over the other N-acetyl-l-amino acid salts studied in CHCl3 containing 0.1% DMSO, has been designed and synthesized. Moreover, the complexation-induced change in emission characteristics of 1 distinguishes the amino acid salts examined from their conjugate acids. Interaction studies were performed by UV–vis, fluorescence and NMR spectroscopic methods. A simple neutral naphthyridine –based chemosensor 1, which selectively recognizes the tetrabutylammonium salt of N-acetyl-l-proline in CHCl3 containing 0.1% DMSO, has been designed and synthesized. The complexation-induced change in emission characteristics of 1 distinguishes the amino acid salts from their conjugate acids.

  我们设计并合成了一种简单的基于中性萘啶的化学传感器 1，它能在含有 0.1% DMSO 的 CHCl3 中选择性地识别 N-乙酰基-l-脯氨酸的四丁基铵盐，而不是所研究的其他 N-乙酰基-l-氨基酸盐。此外，络合引起的 1 发射特性的变化将所研究的氨基酸盐与它们的共轭酸区分开来。通过紫外-可见光、荧光和核磁共振光谱方法进行了相互作用研究。设计并合成了一种简单的基于中性萘啶的化学传感器 1，它能在含有 0.1% DMSO 的 中选择性地识别 N-乙酰-l-脯氨酸的四丁基铵盐。1 的络合诱导发射特性变化可将氨基酸盐与其共轭酸区分开来。