3',3',6',6'-tetramethyl-3',4',6',7'-tetrahydro-1'H,2H-spiro-[acenaphthylene-1,9'-acridine]-1',2,8'(2'H,5'H,10'H)-trione | 1197995-07-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3',3',6',6'-tetramethyl-3',4',6',7'-tetrahydro-1'H,2H-spiro-[acenaphthylene-1,9'-acridine]-1',2,8'(2'H,5'H,10'H)-trione
• CAS: 1197995-07-5
• 化学式: C₂₈H₂₇NO₃
• 分子量: 425.527
• InChiKey: XTRXAKOHQTWVOK-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  5,5-二甲基-1,3-环己二酮 、 苊醌 在 苯乙腈 、 氯化铵 作用下， 以 水 为溶剂， 反应 0.17h， 以60%的产率得到3',3',6',6'-tetramethyl-3',4',6',7'-tetrahydro-1'H,2H-spiro-[acenaphthylene-1,9'-acridine]-1',2,8'(2'H,5'H,10'H)-trione
  参考文献：
  名称：

  Ammonium salt catalyzed multicomponent transformation: simple route to functionalized spirochromenes and spiroacridines

  摘要：

  The combination of isatin or acenaphthoquinone, an activated methylene reagent, and 1,3-dicarbonyl compounds in the presence of catalytic ammonium chloride was found to be a suitable and efficient method for the synthesis of the biologically important spirooxindoles. (c) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.08.070

文献信息

• A highly active FeNi3–SiO2 magnetic nanoparticles catalyst for the preparation of 4H-benzo[b]pyrans and Spirooxindoles under mild conditions
  作者：Mohammad Ali Nasseri、Seyed Mohsen Sadeghzadeh

  DOI：10.1007/s13738-013-0243-3

  日期：2013.10

  A green and efficient method for the synthesis of various 4H-benzo[b]pyrans and Spirooxindoles in the presence of FeNi3–SiO2 as the nanocatalyst at room temperature is reported. High catalytic activity and ease of recovery from the reaction mixture using an external magnet, and several reuse times without significant losses in performance are additional eco-friendly attributes of this catalytic system

  据报道，在室温下，在FeNi 3 -SiO 2作为纳米催化剂的存在下，一种绿色高效的合成各种4H-苯并[b]吡喃和螺恶唑的方法。高催化活性和使用外部磁体从反应混合物中回收的容易性，以及多次重复使用而不会显着降低性能，是该催化系统的其他环保特性。