4-羟基-2,5-二甲基噻吩-3(2H)-酮 | 26494-10-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 乙烯基硫酯
• 中文名称: 4-羟基-2,5-二甲基噻吩-3(2H)-酮
• 英文名称: 4-hydroxy-2,5-dimethyl-2,3-dihydrothiophen-3-one
• 英文别名: 4-hydroxy-2,5-dimethyl-2,3-dihydrothiophene-3-one；4-Hydroxy-2,5-dimethylthiophen-3(2H)-one；4-hydroxy-2,5-dimethylthiophen-3-one
• CAS: 26494-10-0
• 化学式: C₆H₈O₂S
• 分子量: 144.194
• InChiKey: LMGFTFOLCQQHHC-UHFFFAOYSA-N

物化性质

• LogP：
  1.447 (est)
• 保留指数：
  1158

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  62.6
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2934999090

反应信息

• 作为反应物：
  描述：

  4-羟基-2,5-二甲基噻吩-3(2H)-酮 、 二氨基马来腈 以 乙腈 为溶剂， 反应 126.0h， 以3%的产率得到2,3-dicyano-5,7-bismethylthieno[3,4-b]pyrazine
  参考文献：
  名称：

  邻醌杂环：2,3-二氰基-5,7-双甲基噻吩并[3,4-b]吡嗪的合成和晶体结构。

  摘要：

  2,3-Dicyano-5,7-bismethylthieno[3,4-b]pyrazine (5)，是 S-亲核试剂与 5,6-di(1-bromoethyl)pyrazine-2 反应的次要产物,3-二甲腈 (3)，或来自 4-羟基-2,5-二甲基-2,3-二氢噻吩-3-酮 (4) 与二氨基马来腈的缩合。X射线衍射证实了化合物5的分子结构。电荷的部分分离导致平面分子在均匀平行堆叠中的施主-受主型排列，在 100 K 时的面间距为 3.334(2) A。

  DOI：

  10.3390/12081623
• 作为产物：
  描述：

  3-己炔-2,5-二醇 在 吡啶 、 sodium sulfide 、 potassium permanganate 、 碳酸氢钠 、 magnesium sulfate 作用下， 以 乙醇 、 丙酮 为溶剂， 反应 18.0h， 生成 4-羟基-2,5-二甲基噻吩-3(2H)-酮
  参考文献：
  名称：

  Identification of Potent Aroma Compounds in Thermally Treated Mixtures of Glucose/Cysteine and Rhamnose/Cysteine Using Aroma Extract Dilution Techniques

  摘要：

  Application of an aroma extract dilution analysis on extracts prepared from either thermally treated solutions (20 min, 145 degrees C) of glucose/cysteine (I) or rhamnose/cysteine (II) led to the identification of 2-furfurylthiol (roasty, coffee-like), 5-acetyl-2,3-dihydro-1,4-thiazine (roasty), 3-mercapto-2-butanone (sulfury, rotten), 3-mercapto-2-pentanone (catty), and 4-hydroxy-2,5-dimethyl-3(2H)-furanone (caramel-like) with the highest odor activities among the 34 odor-active volatiles detected in I. In II, 4-hydroxy-2,5-dimethyl-3(2H)-furanone, 3-hydroxy-6-methyl-2(2H)-pyranone (seasoning-like), 5-methyl-2-furfurylthiol (roasty, coffee-like), 2-furfurylthiol, and 5-acetyl-2,3-dihydro-1,4-thiazine appeared with the highest flavor dilution (FD) factors among the 18 compounds detected by HRGC/O. Among the flavor compounds identified, 2-propionyl-2-thiazoline is reported for the first time among the flavors of Maillard model reactions or foods, respectively. The odorant elicited an intense roasty, popcorn-like odor at the low odor threshold of 0.07 ng/L in air.

  DOI：

  10.1021/jf960456t

文献信息

• Exocellular polysaccharide produced by streptococcus thermophilus
  申请人：SOCIETE DES PRODUITS NESTLE S.A.

  公开号：EP0889135A1

  公开（公告）日：1999-01-07

  The invention relates to a new isolated exo-polysaccharide originating from Streptococcus thermophilus consisting of essentially D-galactose, L-rhamnose and D-glucose in a molar ratio of 3:2:1, and optionally consisting of the following repeat structure. This polysaccharide may be used in flavour reactions, and for the preparation of a food, cosmetic or pharmaceutical composition intended for inhibiting β-galactoside specific lectins.

  本发明涉及一种源自嗜热链球菌的新分离外多糖，主要由 D-半乳糖、L-鼠李糖和 D-葡萄糖组成，摩尔比为 3:2:1，并可选择由以下重复结构组成。这种多糖可用于调味反应，也可用于制备抑制 β-半乳糖苷特异性凝集素的食品、化妆品或药物组合物。
• Extracellular polysaccharide from Gluconacetobacter spp
  申请人：SOCIETE DES PRODUITS NESTLE S.A.

  公开号：EP1203822A1

  公开（公告）日：2002-05-08

  The present invention is related to a bacterial extracellular polysaccharide, which has a xanthan-like structure with a non-cellulosic backbone with 4-beta and 6-beta linkages, non or very little acetylation and having at least one sidechain per repeating unit, an isolated Gluconacetobacter spp. strain producing such polysaccharide and to their use in various food or pet food products or for the preparation of food or pet food products.

  本发明涉及一种细菌胞外多糖，这种多糖具有类似黄原胶的结构，其非纤维素骨架上有 4-beta 和 6-beta 连接，没有或很少有乙酰化，每个重复单元至少有一条侧链，还涉及一种能产生这种多糖的分离的葡萄糖乙酰杆菌属菌株，以及它们在各种食品或宠物食品中的用途或用于制备食品或宠物食品。
• HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR
  申请人：Meiji Seika Kaisha, Ltd.

  公开号：EP1602354A1

  公开（公告）日：2005-12-07

  The present invention intends to provide a composition for hair treatment containing γ-polyglutamic acid or a salt thereof, a hair cosmetic for damaged hair containing such a composition, and their uses. The composition for hair treatment containing γ-polyglutamic acid or a salt thereof and the hair cosmetic for damaged hair of the present invention have excellent improvement effects on the strength and frictional force of hair, so that they can provide tension, elasticity, or the like to damage hair to prevent or alleviate split hair and broken hair as well as improvements in combing and touch. Furthermore, they also exert effects of moisture retention inherent to γ-polyglutamic acid or a salt thereof, preventing or improving effects on the generation of dandruff on the basis of such effects, preventing effects on the feeling of stickiness or creak, and various effectiveness including appropriate residual tendency to hair in a simultaneous manner, respectively.

  本发明旨在提供一种含有γ-聚谷氨酸或其盐的头发治疗组合物、一种含有这种组合物的用于受损头发的护发化妆品及其用途。本发明的含有γ-聚谷氨酸或其盐的头发治疗组合物和用于受损头发的护发化妆品对头发的强度和摩擦力有很好的改善效果，因此它们可以为受损头发提供张力、弹性等，以防止或减轻头发分叉和断裂，并改善梳理和触感。此外，它们还能分别发挥γ-聚谷氨酸或其盐固有的保湿效果、在此基础上防止或改善头皮屑产生的效果、防止粘腻感或吱吱作响的效果，以及包括同时对头发产生适当残留倾向在内的各种功效。
• Bacterial extracellular polysaccharide, gluconacetobacter spp. strain producing it and their use in food or pet food products
  申请人：NESTEC S.A.

  公开号：US20030219512A1

  公开（公告）日：2003-11-27

  The present invention relates to a novel non-cellulosic bacterial extracellular polysaccharide, produced from the Gluconacetobacter spp. strain, and methods of using the polysaccharide and strain in the preparation of various foods.

  本发明涉及一种新型非纤维素细菌胞外多糖，由 Gluconacetobacter spp.菌株产生，以及将该多糖和菌株用于制备各种食品的方法。
• Cosmetic composition and production thereof
  申请人：Kawasaki Yuji

  公开号：US20060018867A1

  公开（公告）日：2006-01-26

  It has been desired to develop a highly preservative and antibacterial cosmetic composition that can easily be applied to both emulsion and non-emulsion type cosmetics. It has also been desired to develop a method of improving a preservative and/or antibacterial effect(s) of a cosmetic composition comprising polyorganosiloxane-containing epsilon-polylysine and thereby reducing the amount of antibacterial preservative agent to be used. There is provided a cosmetic composition comprising one or a combination of two or more of polyorganosiloxane-containing epsilon-polylysine compounds obtained by reacting epsilon-polylysine with polyorganosiloxane or a physiologically acceptable salt thereof, and polyhydric alcohol.

  人们一直希望开发一种高防腐性和抗菌性的化妆品组合物，这种组合物既可用于乳液型化妆品，也可用于非乳液型化妆品。此外，还希望开发一种方法，以改善含有聚有机硅氧烷的ε-聚赖氨酸的化妆品组合物的防腐和/或抗菌效果，从而减少抗菌防腐剂的用量。本发明提供了一种化妆品组合物，该组合物包含一种或两种以上的含聚有机硅氧烷的ε-聚赖氨酸化合物的组合，这些ε-聚赖氨酸化合物是通过ε-聚赖氨酸与聚有机硅氧烷或其生理上可接受的盐以及多元醇反应而得到的。

表征谱图