[(2-Hexylcyclopentylidene)amino]thiourea

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: [(2-Hexylcyclopentylidene)amino]thiourea
• 英文别名: [(E)-(2-hexylcyclopentylidene)amino]thiourea
• 化学式: C₁₂H₂₃N₃S
• mdl: MFCD00571007
• 分子量: 241.4
• InChiKey: OWGUSBISUVLUJF-SDNWHVSQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.833
• 拓扑面积：
  82.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• THIAZOLE-BASED INHIBITORS OF SCAVENGER RECEPTOR BI
  申请人：Dockendorff Chris

  公开号：US20160060254A1

  公开（公告）日：2016-03-03

  This application describes compounds and methods that can inhibit Scavenger receptor class B, type I (SR-BI) activity, which compounds and methods can used, for example, to mediate high-density lipoprotein (HDL) lipid uptake and treat hepatitis C viral infections.

  这个应用程序描述了可以抑制清道夫受体B类I型（SR-BI）活性的化合物和方法，这些化合物和方法可以用于介导高密度脂蛋白（HDL）脂质摄取和治疗丙型肝炎病毒感染。
• Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases
  申请人：Cenix Bioscience GmbH

  公开号：EP1832283A1

  公开（公告）日：2007-09-12

  The present invention relates to the use of inhibitors of scavenger receptor class proteins, in particular ScarB1 for the production of a medicament for treatment of and/or prophylaxis against infections, involving liver cells and/or hematopoietic cells, in particular malaria.

  本发明涉及使用清道夫受体类蛋白，特别是 ScarB1 的抑制剂来生产治疗和/或预防涉及肝细胞和/或造血细胞，特别是疟疾的感染的药物。
• NANOSTRUCTURES FOR TREATING CANCERS
  申请人：Northwestern University

  公开号：EP2817024B1

  公开（公告）日：2019-07-10
• METHODS FOR TREATING AND/OR LIMITING DEVELOPMENT OF DIABETES
  申请人：BioCrine AB

  公开号：EP2936151B1

  公开（公告）日：2018-07-18
• Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases
  申请人：Hannus Michael

  公开号：US20090324580A1

  公开（公告）日：2009-12-31

  The present invention relates to the use of inhibitors of scavenger receptor class proteins, in particular ScarB1 for the production of a medicament for treatment of and/or prophylaxis against infections, involving liver cells and/or hematopoietic cells, in particular malaria.