(+)-2,2'-di(2-methoxyethoxymethyloxy)binaphthyl | 147749-78-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (+)-2,2'-di(2-methoxyethoxymethyloxy)binaphthyl
• CAS: 147749-78-8
• 化学式: C₂₈H₃₀O₆
• 分子量: 462.543
• InChiKey: ZTCVFBKUALJXMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.66
• 重原子数：
  34.0
• 可旋转键数：
  13.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  55.38
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  (+)-2,2'-di(2-methoxyethoxymethyloxy)binaphthyl 在 正丁基锂 、 氢溴酸 、 溴 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 18.25h， 生成 (S)-6-bromo-3,3'-dimethyl-2,2'-dihydroxy-1,1'-binaphthyl
  参考文献：
  名称：

  Monofunctional chiral crowns. Part 1

  摘要：

  A siloxane oligomer bearing a chiral crown with high affinity for alpha-amino acids has been synthesised. The host is a modified form of a coronand first prepared by Cram, in which two 1,1'-binaphthol system are linked through the oxygen atoms at the 2,2'-positions to form a 22-membered ring system containing six ether oxygen atoms attached to each other by four ethylene units. This was selectively mono-alkenylated to form an undec-10-en-1-yl derivative, which was bonded to linear siloxanes [HSiMe2O(SiMe2O)nSiMe2H] and [Me3SiO(Me2SiO)x(MeHSiO)ySiMe3] with total chain lengths of ca 4 and 200 Si atoms respectively, via a Pt catalysed hydrosilylation reaction.

  DOI：

  10.1016/s0040-4020(01)86291-8
• 作为产物：
  描述：

  2-甲氧基乙氧基甲基氯 、 S-1,1'-联-2-萘酚 在 sodium hydride 作用下， 生成 (+)-2,2'-di(2-methoxyethoxymethyloxy)binaphthyl
  参考文献：
  名称：

  Monofunctional chiral crowns. Part 1

  摘要：

  A siloxane oligomer bearing a chiral crown with high affinity for alpha-amino acids has been synthesised. The host is a modified form of a coronand first prepared by Cram, in which two 1,1'-binaphthol system are linked through the oxygen atoms at the 2,2'-positions to form a 22-membered ring system containing six ether oxygen atoms attached to each other by four ethylene units. This was selectively mono-alkenylated to form an undec-10-en-1-yl derivative, which was bonded to linear siloxanes [HSiMe2O(SiMe2O)nSiMe2H] and [Me3SiO(Me2SiO)x(MeHSiO)ySiMe3] with total chain lengths of ca 4 and 200 Si atoms respectively, via a Pt catalysed hydrosilylation reaction.

  DOI：

  10.1016/s0040-4020(01)86291-8