tert-butyl 4-(7-hydroxy-6-methoxyquinazolin-4-yl)piperazinecarboxylate | 401819-62-3
中文名称
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中文别名
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英文名称
tert-butyl 4-(7-hydroxy-6-methoxyquinazolin-4-yl)piperazinecarboxylate
英文别名
4-(7-hydroxy-6-methoxy-4-quinazolinyl)-1-piperazinecarboxylic acid tert-butyl ester；tert-butyl-4-(7-hydroxy-6-methoxyquinazolin-4-yl)piperazine-1-carboxylate；tert-butyl 4-(7-hydroxy-6-methoxyquinazolin-4-yl)piperazine-1-carboxylate
CAS
401819-62-3
化学式
C18H24N4O4
mdl
——
分子量
360.413
InChiKey
POVOVTPBLTXOPE-UHFFFAOYSA-N
BEILSTEIN
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EINECS
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
物化性质
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熔点：247-248 °C(Solv: ethyl acetate (141-78-6))
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沸点：538.3±50.0 °C(Predicted)
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密度：1.273±0.06 g/cm3(Predicted)
计算性质
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辛醇/水分配系数(LogP)：2.3
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重原子数：26
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可旋转键数：4
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环数：3.0
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sp3杂化的碳原子比例：0.5
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拓扑面积：88
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氢给体数：1
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氢受体数：7
上下游信息
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上游原料
中文名称 英文名称 CAS号 化学式 分子量 —— 4-(7-benzyloxy-6-methoxy-4-quinazolinyl)-1-piperazinecarboxylic acid tert-butyl ester 205259-42-3 C25H30N4O4 450.538 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— 4-(7-ethoxy-6-methoxy-4-quinazolinyl)-1-piperazinecarboxylic acid tert-butyl ester 205259-38-7 C20H28N4O4 388.467 —— 4-(7-isopropoxy-6-methoxy-4-quinazolinyl)-1-piperazinecarboxylic acid tert-butyl ester 205259-43-4 C21H30N4O4 402.494 —— 4-(6-methoxy-7-propoxy-4-quinazolinyl)-1-piperazinecarboxylic acid tert-butyl ester 634198-10-0 C21H30N4O4 402.494 —— 4-(7-allyloxy-6-methoxy-4-quinazolinyl)-1-piperazinecarboxylic acid tert-butyl ester 634198-11-1 C21H28N4O4 400.478 —— tert-butyl-4-[6-methoxy-7-(2-chloroethoxy)quinazolin-4-yl]piperazinecarboxylate 401819-63-4 C20H27ClN4O4 422.912 —— 4-(6-methoxy-7-propargyloxy-4-quinazolinyl)-1-piperazinecarboxylic acid tert-butyl ester 634198-12-2 C21H26N4O4 398.462 —— 4-[6-methoxy-7-(2-methoxyethoxy)-4-quinazolinyl]-1-piperazinecarboxylic acid tert-butyl ester 461429-64-1 C21H30N4O5 418.493 —— 4-[7-(2-ethoxyethoxy)-6-methoxy-4-quinazolinyl]-1-piperazinecarboxylic acid tert-butyl ester 634198-14-4 C22H32N4O5 432.52 —— 4-[7-(3-chloropropoxy)-6-methoxy-quinazolin-4-yl]piperazine-1-carboxylic acid tert-butyl ester 461429-76-5 C21H29ClN4O4 436.939 —— 4-(7-butoxy-6-methoxy-4-quinazolinyl)-1-piperazinecarboxylic acid tert-butyl ester 634198-13-3 C22H32N4O4 416.52 —— Tert-butyl 4-[7-(3-ethylsulfanylpropoxy)-6-methoxyquinazolin-4-yl]piperazine-1-carboxylate 779330-96-0 C23H34N4O4S 462.613 —— Tert-butyl 4-[7-(3-butylsulfanylpropoxy)-6-methoxyquinazolin-4-yl]piperazine-1-carboxylate 1026014-50-5 C25H38N4O4S 490.667 —— 4-{6-Methoxy-7-[3-(3-methyl-butylsulfanyl)-propoxy]-quinazolin-4-yl}-piperazine-1-carboxylic acid tert-butyl ester 1026961-37-4 C26H40N4O4S 504.694 —— 4-[6-Methoxy-7-(3-piperidin-1-yl-propoxy)-quinazolin-4-yl]-piperazine-1-carboxylic acid tert-butyl ester 741702-11-4 C26H39N5O4 485.627 —— tert-butyl-4-[6-methoxy-7-(2-piperidylethoxy)quinazolin-4-yl]piperazinecarboxylate 401819-64-5 C25H37N5O4 471.6 —— 4-[7-(3-Ethanesulfonyl-propoxy)-6-methoxy-quinazolin-4-yl]-piperazine-1-carboxylic acid tert-butyl ester 779331-89-4 C23H34N4O6S 494.612 —— 6-Methoxy-7-(2-methoxy-ethoxy)-4-piperazin-1-yl-quinazoline 461429-70-9 C16H22N4O3 318.376 6-甲氧基-7-[2-(4-甲基-哌嗪-1-基)-乙氧基]-4-哌嗪-1-基-喹唑啉 6-Methoxy-7-[2-(4-methylpiperazin-1-yl)ethoxy]-4-piperazin-1-ylquinazoline 1026962-77-5 C20H30N6O2 386.497 —— 6-methoxy-4-(piperazin-1-yl)-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline 741702-17-0 C20H29N5O2 371.483 —— 4-[2-(6-Methoxy-4-piperazin-1-ylquinazolin-7-yl)oxyethyl]morpholine 741700-15-2 C19H27N5O3 373.455 —— 6-methoxy-4-(piperazin-1-yl)-7-(3-(piperidin-1-yl)propoxy)quinazoline 461429-53-8 C21H31N5O2 385.509 —— 6-Methoxy-4-piperazin-1-yl-7-(2-pyrrolidin-1-ylethoxy)quinazoline 876854-13-6 C19H27N5O2 357.456 —— 6-methoxy-7-(2-piperidylethoxy)-4-piperazinylquinazoline 401819-61-2 C20H29N5O2 371.483 —— 4-[3-(6-Methoxy-4-piperazin-1-ylquinazolin-7-yl)oxypropyl]morpholine 741701-46-2 C20H29N5O3 387.482 6-甲氧基-4-哌嗪-1-基-7-(2-硫代吗啉-4-基-乙氧基)-喹唑啉 4-[2-(6-Methoxy-4-piperazin-1-ylquinazolin-7-yl)oxyethyl]thiomorpholine 1026857-68-0 C19H27N5O2S 389.522 —— 1-[2-(6-Methoxy-4-piperazin-1-ylquinazolin-7-yl)oxyethyl]piperidin-4-ol 1026948-33-3 C20H29N5O3 387.482 —— 6-Methoxy-4-piperazin-1-yl-7-(3-propylsulfonylpropoxy)quinazoline 1026845-73-7 C19H28N4O4S 408.522 —— 4-(4-cyclopentylpiperazin-1-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline —— C25H37N5O2 439.601 —— 7-(3-Butylsulfonylpropoxy)-6-methoxy-4-piperazin-1-ylquinazoline 1026792-32-4 C20H30N4O4S 422.549 —— 6-Methoxy-7-[3-(2-methylpropylsulfonyl)propoxy]-4-piperazin-1-ylquinazoline 1027248-90-3 C20H30N4O4S 422.549 —— 6-Methoxy-4-piperazin-1-yl-7-[2-(triazol-2-yl)ethoxy]quinazoline 741700-42-5 C17H21N7O2 355.399 —— 4-(7-Ethoxy-6-methoxy-4-quinazolinyl)-N-(4-phenoxyphenyl)-1-piperazinecarboxamide —— C28H29N5O4 499.569 —— 6-Methoxy-4-piperazin-1-yl-7-[3-(triazol-2-yl)propoxy]quinazoline 741702-21-6 C18H23N7O2 369.426 —— 4-(7-Isopropoxy-6-methoxy-4-quinazolinyl)-N-(4-phenoxyphenyl)-1-piperazinecarboxamide —— C29H31N5O4 513.596 —— 4-[2-(6-Methoxy-4-piperazin-1-ylquinazolin-7-yl)oxyethyl]-1,4-thiazinane 1,1-dioxide 741700-74-3 C19H27N5O4S 421.52 —— N-(4-cyanophenyl){4-[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]piperazinyl}carboxamide —— C24H26N6O4 462.508 —— 7-[3-(4,4-Difluoropiperidin-1-yl)propoxy]-6-methoxy-4-piperazin-1-ylquinazoline 741702-27-2