1-(2'-hydroxy-5'-methylphenyl)-1-dodecanone | 103582-41-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 1-(2'-hydroxy-5'-methylphenyl)-1-dodecanone
• 英文别名: E-1-(2'-hydroxy-5'-methylphenyl)-1-dodecanone oxime；2-hydroxy-5-methyl-phenyl-dodecan-1-on-oxim；2-hydroxy-5-methyllaurophenone oxime；1-(2-Hydroxy-5-methylphenyl)dodecan-1-one oxime；2-[(E)-N-hydroxy-C-undecylcarbonimidoyl]-4-methylphenol
• CAS: 103582-41-8
• 化学式: C₁₉H₃₁NO₂
• 分子量: 305.461
• InChiKey: OOXQDZTUGOJLHK-CZIZESTLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  22
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  52.8
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-(2'-hydroxy-5'-methylphenyl)-1-dodecanone 在 五氯化磷 、 硫酸 作用下， 生成 月桂酸 、 N-(2'-hydroxy-5'-methylphenyl)dodecanoamide 、 邻氨基对甲苯酚
  参考文献：
  名称：

  Krzyzanowska, Ewa; Olszanowski, A.; Juskowiak, M., Journal fur praktische Chemie (Leipzig 1954), 1989, vol. 331, # 4, p. 617 - 630

  摘要：

  DOI：
• 作为产物：
  描述：

  1-(2-hydroxy-5-methyl-phenyl)-dodecan-1-one 在 吡啶 、 盐酸羟胺 作用下， 以 甲醇 为溶剂， 反应 5.0h， 以85%的产率得到1-(2'-hydroxy-5'-methylphenyl)-1-dodecanone
  参考文献：
  名称：

  Krzyzanowska, Ewa; Olszanowski, A.; Juskowiak, M., Journal fur praktische Chemie (Leipzig 1954), 1989, vol. 331, # 4, p. 617 - 630

  摘要：

  DOI：

文献信息

• Mass spectra of 1-(2′-hydroxy-5′-alkylphenyl)-1-alkanone (E)-oximes
  作者：Marek Łozyński、Ewa Krzyzanowska

  DOI：10.1002/oms.1210210108

  日期：1986.1

  AbstractThe mass spectra of 1‐(2′‐hydroxy‐5′‐alkylphenyl)‐1‐ethanone (E)‐oximes 1–6 and 1‐(2′‐hydroxy‐5′‐methylphenyl)‐1‐alkanone (E)‐oximes 7–12 are given and the major fragmentation pathways discussed. The simultaneous loss of water and alkyl moieties from the molecular ion indicates that a skeletal rearrangement take place and a cycloheptatrienyloheterocyclic system is formed. The McLafferty rearrangement, γ‐fission in the side aliphatic chain and oxygen expulsion are discussed with evidence being drawn from accurate mass measurements, metastable ions and comparison with mass spectral data of related compounds.
• Regulation of mammalian keratinous tissue using skin and/or hair care actives
  申请人：Millikin Lynn Cheri

  公开号：US20080069784A1

  公开（公告）日：2008-03-20

  Personal care compositions containing an active selected from the group consisting of Lauryl p-Cresol Ketoxime, Bis-abolol and ginger extract, 4-(1-Phenylethyl)1,3-benzenediol, Lupin ( Lupinus albus ) oil & wheat ( Triticum vulgare ) germ oil unsaponifiables, Hydrolyzed lupin protein, Extract of L-lysine and L-arginine peptides, Oil soluble vitamin C, Evodia rutaecarpa fruit extract, Zinc pidolate and zinc PCA, Unsaponifiable fraction of olive ( olea Europaea) oil, Alpha-linoleic acid, p-thymol, and combinations thereof are provided. Methods for regulating the condition of mammalian keratinous tissue by topically applying the personal care compositions are also provided.
• Krzyzanowska, Ewa; Olszanowski, A.; Juskowiak, M., Journal fur praktische Chemie (Leipzig 1954), 1989, vol. 331, # 4, p. 617 - 630
  作者：Krzyzanowska, Ewa、Olszanowski, A.、Juskowiak, M.

  DOI：——

  日期：——