propionic acid-(3β-hydroxy-17α-methyl-androsten-(5)-yl-(17β)-ester) | 35800-60-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: propionic acid-(3β-hydroxy-17α-methyl-androsten-(5)-yl-(17β)-ester)
• 英文别名: Propionsaeure-(3β-hydroxy-17α-methyl-androsten-(5)-yl-(17β)-ester)；(10R)-3c-Hydroxy-17c-propionyloxy-10r.13c.17t-trimethyl-(8cH.9tH.14tH)-Δ⁵-tetradecahydro-1H-cyclopenta[a]phenanthren；17-Methyl,17ss-Diol Androst-5-ene-3ss-17-propionate; (3S,8R,9S,10R,13S,14S,17S)-3-Hydroxy-10,13,17-trimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl Propionate；[(3S,8R,9S,10R,13S,14S,17S)-3-hydroxy-10,13,17-trimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] propanoate
• CAS: 35800-60-3
• 化学式: C₂₃H₃₆O₃
• 分子量: 360.537
• InChiKey: HFWPYYYPRQGIFO-ZGIWMXSJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  propionic acid-(3β-hydroxy-17α-methyl-androsten-(5)-yl-(17β)-ester) 在 chromium(VI) oxide 、 溴 、 溶剂黄146 作用下， 生成 17α-methyl-17β-propionyloxy-androst-4-en-3-one
  参考文献：
  名称：

  Kuwada; Miyasaka, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1938, vol. 58, p. 319,322; dtsch. Ref. S. 59

  摘要：

  DOI：
• 作为产物：
  描述：

  美雄醇二丙酸酯 在 氢氧化钾 作用下， 生成 propionic acid-(3β-hydroxy-17α-methyl-androsten-(5)-yl-(17β)-ester)
  参考文献：
  名称：

  Kuwada; Miyasaka, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1938, vol. 58, p. 319,322; dtsch. Ref. S. 59

  摘要：

  DOI：

文献信息

• Compositions, Methods and Uses for Treating Gender-Biased Immune Disorders
  申请人：Biocopea Limited

  公开号：US20160008376A1

  公开（公告）日：2016-01-14

  The present specification discloses compositions comprising at least one therapeutic compound capable of modulating a level and/or activity of a hormone and methods and uses for treating a gender-biased immune disorder using such compositions.
• [EN] COMPOSITIONS, METHODS AND USES FOR TREATING GENDER-BIASED IMMUNE DISORDERS<br/>[FR] COMPOSITIONS, PROCÉDÉS ET UTILISATIONS POUR LE TRAITEMENT DE TROUBLES IMMUNITAIRES DÉPENDANT DU SEXE
  申请人：BIOCOPEA LTD

  公开号：WO2016005599A1

  公开（公告）日：2016-01-14

  The present specification discloses compositions comprising at least one therapeutic compound capable of modulating a level and/or activity of a hormone and methods and uses for treating a gender-biased immune disorder using such compositions.