[Cu2(1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol(-1H))2(OAc)2] | 796073-45-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: [Cu2(1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol(-1H))2(OAc)2]
• 英文别名: [Cu2(propranolol(-1H))(OAc)2]；dicopper;1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-olate;diacetate
• CAS: 796073-45-5
• 化学式: C₃₆H₄₆Cu₂N₂O₈
• 分子量: 761.862
• InChiKey: UBDLPSOZNCVCTA-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  copper(II) acetate monohydrate 、 Inderal 在 NaOH 作用下， 以 甲醇 、 水 为溶剂， 以70%的产率得到[Cu2(1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol(-1H))2(OAc)2]
  参考文献：
  名称：

  Synthesis and Characterization of Metal Complexes of Acebutolol, Atenolol, and Propranolol Antihypertension Drugs

  摘要：

  The complexation of two transition metal ions with the beta-blocker drugs acebutolol (HL1), atenolol (HL2), and propranolol (HL3) was studied in methanol and acetonitrile media at M:L (metal: ligand) molar ratio from 1:1 to 1:10. Cu(II) complexes with ligands having the stoichiometric ratio 1:4 (mononuclear copper(H) complexes) and 1:1 (binuclear copper(II) complexes) were prepared. The analytical data show that the metal to ligand ratio in the mononuclear Co(II) complexes was 1:2. The complexes were characterized on the basis of analytical data, magnetic moments, atomic absorption, infrared and electronic spectral data. Molar conductivities of the complexes at room temperature were measured. The conductivity values of the mononuclear Cu(II) complexes indicate weak electrolyte behavior, whereas the binuclear Cu(II) and mononuclear Co(II) complexes are non-electrolytes. The thermal properties of all complexes have been studied by the DTA and TG.

  DOI：

  10.1081/sim-120039270