摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 7-Pentofuranosyl-7h-pyrrolo[2,3-d]pyrimidin-4-ol

    7-Pentofuranosyl-7h-pyrrolo[2,3-d]pyrimidin-4-ol | 2862-16-0

    分子结构分类

    有机化合物 - 核苷、核苷酸和类似物 - 吡咯并嘧啶核苷和核苷酸
    中文名称
    ——
    中文别名
    ——
    英文名称
    7-Pentofuranosyl-7h-pyrrolo[2,3-d]pyrimidin-4-ol
    英文别名
    7-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-pyrrolo[2,3-d]pyrimidin-4-one
    7-Pentofuranosyl-7h-pyrrolo[2,3-d]pyrimidin-4-ol化学式
    CAS
    2862-16-0
    化学式
    C11H13N3O5
    mdl
    ——
    分子量
    267.24
    InChiKey
    DPRSKJHWKNHBOW-UHFFFAOYSA-N
    BEILSTEIN
    ——
    EINECS
    ——
    • 物化性质
    • 计算性质
    • ADMET
    • 安全信息
    • SDS
    • 制备方法与用途
    • 上下游信息
    • 反应信息
    • 文献信息
    • 表征谱图
    • 同类化合物
    • 相关功能分类
    • 相关结构分类

    物化性质

    • 熔点：
      242.5°C
    • 沸点：
      410.42°C (rough estimate)
    • 密度：
      1.3329 (rough estimate)

    计算性质

    • 辛醇/水分配系数(LogP)：
      -1.8
    • 重原子数：
      19
    • 可旋转键数：
      2
    • 环数：
      3.0
    • sp3杂化的碳原子比例：
      0.45
    • 拓扑面积：
      116
    • 氢给体数：
      4
    • 氢受体数：
      5

    SDS

    SDS：5115edd658699e1610f2d2ab7e3e526f
    查看

    文献信息

    • ANTI-FLAVIVIRUS COMPOUNDS AND METHODS OF USE
      申请人：FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
      公开号：US20200197369A1
      公开（公告）日：2020-06-25
      The present invention concerns the use of compounds and compositions for the treatment or prevention of Flavivirus infections, such as dengue virus infections and Zika virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus and Zika virus infection, by administering a compound or composition of the invention, to a subject in need thereof; methods for inhibiting Flavivirus infections, such as dengue virus and Zika virus infections, in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits useful for treating or preventing Flavivirus infections, such as dengue virus and Zika virus infections.
    • METHOD FOR INHIBITING ZIKA VIRUS INFECTION
      申请人：FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
      公开号：US20220323420A1
      公开（公告）日：2022-10-13
      The present invention concerns the use of compounds and compositions for the treatment or prevention of Flavivirus infections, such as dengue virus infections and Zika virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus and Zika virus infection, by administering a compound or composition of the invention, to a subject in need thereof; methods for inhibiting Flavivirus infections, such as dengue virus and Zika virus infections, in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits useful for treating or preventing Flavivirus infections, such as dengue virus and Zika virus infections.
    查看更多

    同类化合物

    羧鸟苷霉素 硫代桑吉瓦霉素 桑霉素 核苷Q 杀结核菌素5'-三磷酸酯 杀结核菌素-5'-二磷酸酯 杀结核菌素 木糖基杀结核菌素 N4-环丙基-7-(2-C-甲基-beta-D-呋喃核糖基)-7H-吡咯并[2,3-d]嘧啶-2,4-二胺 7-脱氮-2'-C-乙炔腺苷 7-去氮杂肌苷 7-去氮-AMP 7-{5-O-[二甲基(2-甲基-2-丙基)硅烷基]-2,3-O-异亚丙基-beta-D-来苏呋喃糖基}-4-甲氧基-7H-吡咯并[2,3-d]嘧啶-2-胺 7-beta-D-阿拉伯呋喃糖基-7H-吡咯并[2,3-d]嘧啶-4-胺 7-[3,5-二-O-[(2,4-二氯苯基)甲基]-2-C-甲基-beta-D-呋喃核糖基]-4-氯-7H-吡咯并[2,3-d]嘧啶-2-胺 7-[3,5-二-O-[(2,4-二氯苯基)甲基]-2-C-甲基-beta-D-呋喃核糖基]-4-氯-7H-吡咯并[2,3-d]嘧啶 7-[3,5-二-O-[(2,4-二氯苯基)甲基]-2-C-甲基-beta-D-呋喃核糖基]-4-氯-5-甲基-7H-吡咯并[2,3-d]嘧啶 7-(beta-D-来苏呋喃糖基)-4-甲氧基-7H-吡咯并[2,3-d]嘧啶-2-胺 7-(2-C-甲基-beta-D-呋喃核糖基)-7H-吡咯并[2,3-d]嘧啶-4-胺 6-氯-9-(beta-D-呋喃核糖基)-7-脱氮嘌呤 5-碘代杀结核菌素 5-碘-7-(2-C-甲基-beta-D-呋喃核糖基)-7H-吡咯并[2,3-d]嘧啶-4-胺 5-甲基-7-(2-C-甲基-beta-D-呋喃核糖基)-7H-吡咯并[2,3-d]嘧啶-4-胺 5-溴杀结核菌素 5-氯杀结核菌素 4-氯-7-{5-O-[二甲基(2-甲基-2-丙基)硅烷基]-2,3-O-异亚丙基-beta-D-来苏呋喃糖基}-7H-吡咯并[2,3-d]嘧啶-2-胺 4-氯-7-(2-C-甲基-beta-D-呋喃核糖基)-7H-吡咯并[2,3-d]嘧啶-2-胺 4-氯-7-(2-C-甲基-beta-D-呋喃核糖基)-7H-吡咯并[2,3-d]嘧啶 4-氯-7-(2-C-乙炔基-beta-D-呋喃核糖基)-7H-吡咯并[2,3-d]嘧啶 4-氯-5-甲基-7-(2-C-甲基-beta-D-呋喃核糖基)-7H-吡咯并[2,3-d]嘧啶 4-氨基-7-beta-D-呋喃核糖基-7H-吡咯并[2,3-d]嘧啶-5-甲醇 4-氨基-7-(2-C-甲基-beta-D-呋喃核糖基)-7H-吡咯并[2,3-d]嘧啶-5-甲腈 4-氨基-6-氯-7-[3,4-二羟基-5-(羟基甲基)四氢呋喃-2-基]吡咯并[5,4-d]嘧啶-5-甲酰胺 4-氨基-5-氰基-7-(beta-d-呋喃核糖)吡咯并[2,3-d]嘧啶 4-(甲基硫烷基)-7-(5-O-磷羧基五呋喃糖基)-7H-吡咯并[2,3-d]嘧啶 3-氨基脱氮腺苷二氯铂(II) 2-氨基-7-[(2R,3R,4S,5R)-3,4-二羟基-5-(羟基甲基)四氢呋喃-2-基]-4-氧代-1H-吡咯并[4,5-e]嘧啶-5-甲脒 2-氨基-1,7-二氢-7-beta-D-呋喃核糖基-4H-吡咯并[2,3-d]嘧啶-4-酮 (S)-4-氨基-6-溴-7-((3R,4S,5R)-3,4-二羟基-5-羟基甲基-四氢-呋喃-2-基)-7,7alpha-二氢-4aH-吡咯并[2,3-d]嘧啶-5-甲腈 ((3AR,4R,6R,6AR)-6-(4-氯-7H-吡咯并[2,3-D]嘧啶-7-基)-2,2-二甲基四氢呋喃并[3,4-D][1,3]二氧杂卓-4-基)甲醇 4-amino-7-(4-C-methyl-β-D-ribofuranosyl)-5-(thiophen-2-yl)-7H-pyrrolo[2,3-d]pyrimidine [(R)-(4-chlorophenyl)-[(2S,3S,4R,5R)-5-[4-(3,3-diethoxypropylamino)pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-dihydroxytetrahydrofuran-2-yl]methyl] 4-phenylbenzoate 5-(4-amino-7-((2R,3R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)thiophene-2-carboxylic acid 4-amino-5-iodo-7-(4-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine (S)-[(3aR,4R,6R,6aR)-4-(4-chloropyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-(4-chlorophenyl)methanol (R)-[(3aR,4R,6R,6aR)-4-(4-chloropyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-(4-chlorophenyl)methanol 7-β-D-arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine 5'-phosphate 4-chloro-5-cyano-7-[(2,3,5-tri-O-benzoyl)-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine 3,7-dihydro-5-(prop-1-ynyl)-7-(β-D-ribofuranosyl)-4H-pyrrolo[2,3-d]pyrimidin-4-one 5-propyn-1-yl-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

    热门分子