Bromovinyldeoxycytidine | 74131-09-2

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷
• 英文名称: Bromovinyldeoxycytidine
• 英文别名: 4-amino-5-[(E)-2-bromoethenyl]-1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
• CAS: 74131-09-2
• 化学式: C₁₁H₁₄BrN₃O₄
• 分子量: 332.15
• InChiKey: AKVDSWDYVDOWDW-GIANCMQGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  108
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Novel fluorophosphonate nucleotide derivatives
  申请人：MERRELL DOW PHARMACEUTICALS INC.

  公开号：EP0339161A1

  公开（公告）日：1989-11-02

  This invention relates to fluoromethylphosphonate derivatives of certain nucleosides, to methods for their preparation and to their use as antiviral and antitumoral agents.

  这项发明涉及某些核苷类化合物的氟甲基磷酸酯衍生物，涉及它们的制备方法以及它们作为抗病毒和抗肿瘤药物的用途。
• NEW MEDICAL USE OF GENE AND VECTOR ENCODING A MULTISUBSTRATE DEOXYRIBONUCLEOSIDASE
  申请人：ZGene A/S

  公开号：EP1137764B1

  公开（公告）日：2005-03-02
• METHODS FOR TREATING HERPES VIRUS INFECTIONS
  申请人：Nanobio Corporation

  公开号：EP2280690A2

  公开（公告）日：2011-02-09
• ANTI-AGING AND WRINKLE TREATMENT METHODS USING NANOEMULSION COMPOSITIONS
  申请人：Baker, JR. James R.

  公开号：US20120064136A1

  公开（公告）日：2012-03-15

  The present invention relates to methods for treating, preventing, minimizing, and/or diminishing signs of aging in the skin comprising administering to the subject in need thereof a nanoemulsion composition.
• TOPICAL DELIVERY OF HORMONAL AND NON HORMONAL NANO FORMULATIONS, METHODS OF MAKING AND USING THE SAME
  申请人：NEWGEN BIOPHARMA CORP.

  公开号：US20130224268A1

  公开（公告）日：2013-08-29

  The present invention relates to methods for treating, preventing, minimizing, and/or diminishing signs of aging in the skin comprising topically administering to the subject in need thereof a hormonal nano formulation.