N-[[6-(2,3-dimethoxypropyl)-4-hydroxy-5,5-dimethyloxan-2-yl]-methoxymethyl]-2-hydroxy-2-(2-hydroxy-5,6-dimethyl-4-methylideneoxan-2-yl)acetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: N-[[6-(2,3-dimethoxypropyl)-4-hydroxy-5,5-dimethyloxan-2-yl]-methoxymethyl]-2-hydroxy-2-(2-hydroxy-5,6-dimethyl-4-methylideneoxan-2-yl)acetamide
• 化学式: C₂₄H₄₃NO₉
• 分子量: 489.6
• InChiKey: NNNVJFAPLNIYPF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  34
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  136
• 氢给体数：
  4
• 氢受体数：
  9

文献信息

• ANTICANCER COMPOUNDS
  申请人：Pharma Mar, S.A.

  公开号：US20210317490A1

  公开（公告）日：2021-10-14

  Anticancer compounds of general formula I wherein R 1 to R 4 take various meanings, for use in the treatment of cancer. A novel Labrenzia sp. strain named PHM005 with Accession Deposit Number CECT-9225, a method of producing compounds of the invention and analogues thereof by using the PHM005 strain and the Lab gene cluster codifying the biosynthesis of pederin-like and onnamide-like compounds are also provided.
• [EN] ANTICANCER COMPOUNDS<br/>[FR] COMPOSÉS ANTICANCÉREUX
  申请人：PHARMA MAR SA

  公开号：WO2018167270A1

  公开（公告）日：2018-09-20

  Anticancer compounds of general formula (I), wherein R1 to R4 take various meanings, for use in the treatment of cancer. A novel Labrenziasp. strain named PHM005 with Accession Deposit Number CECT-9225, a method of producing compounds of the invention and analogues thereof by using the PHM005 strain and the Lab gene cluster codifying the biosynthesis of pederin-like and onnamide-like compounds are also provided.