[2-Formyloxy-3-[hydroxy-(2,3,4,5,6-pentahydroxycyclohexyl)oxyphosphoryl]oxypropyl] formate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: [2-Formyloxy-3-[hydroxy-(2,3,4,5,6-pentahydroxycyclohexyl)oxyphosphoryl]oxypropyl] formate
• 英文别名: [2-formyloxy-3-[hydroxy-(2,3,4,5,6-pentahydroxycyclohexyl)oxyphosphoryl]oxypropyl] formate
• 化学式: C₁₁H₁₉O₁₃P
• 分子量: 390.23
• InChiKey: GUBXYMKIJFOYOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.4
• 重原子数：
  25
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  210
• 氢给体数：
  6
• 氢受体数：
  13

文献信息

• COMPOSITIONS COMPRISING CHOLINE AND THEIR USE
  申请人：Société des Produits Nestlé S.A.

  公开号：EP3984532A2

  公开（公告）日：2022-04-20

  The present invention relates to a composition comprising one or more fatty acid derivatives for use in promoting, supporting or optimizing one or more of the following: (i) de novo myelination; (ii) brain structure; (iii) brain connectivity; (iv) intellectual potential; (v) cognitive potential; and (vi) learning potential; (vii) cognitive functioning in an offspring of a female subject, wherein said composition is for administration to the female subject.

  本发明涉及一种包含一种或多种脂肪酸衍生物的组合物，用于促进、支持或优化以下一项或多项： (i) 新生髓鞘； (ii) 大脑结构 (iii) 大脑连通性 (iv) 智力潜能 (v) 认知潜能 (vi) 学习潜能； (vii) 认知功能 女性受试者后代的认知功能，其中所述组合物用于对女性受试者施用。
• Nutritional composition and infant formula for promoting myelination of the brain
  申请人：NESTEC S.A.

  公开号：US11191293B2

  公开（公告）日：2021-12-07

  A synthetic nutritional composition comprising a fatty acid derivative for use to promote, support or optimise de novo myelination, in particular the de novo myelination trajectory, and/or brain structure, and/or brain connectivity, and/or intellectual potential and/or cognitive potential and/or learning potential and/or cognitive functioning in a subject, in particular a formula fed subject.

  一种包含脂肪酸衍生物的合成营养组合物，用于促进、支持或优化受试者（尤其是配方喂养的受试者）的新生髓鞘化，特别是新生髓鞘化轨迹，和/或大脑结构，和/或大脑连通性，和/或智力潜能和/或认知潜能和/或学习潜能和/或认知功能。
• Nutritional composition and infant formula for promoting de novo myelination
  申请人：NESTEC S.A.

  公开号：US11297872B2

  公开（公告）日：2022-04-12

  A synthetic nutritional composition comprising a phospholipid and/or a metabolic precursor and/or metabolite thereof for use to promote, support or optimise de novo myelination, in particular the de novo myelination trajectory, and/or brain structure, and/or brain connectivity, and/or intellectual potential and/or cognitive potential, and/or learning potential and/or cognitive functioning in a subject, in particular a formula fed subject.

  一种由磷脂和/或其代谢前体和/或代谢产物组成的合成营养组合物，用于促进、支持或优化受试者（尤其是配方喂养的受试者）的新生髓鞘化，特别是新生髓鞘化轨迹，和/或大脑结构，和/或大脑连通性，和/或智力潜能和/或认知潜能，和/或学习潜能和/或认知功能。
• Compositions and their use
  申请人：NESTEC S.A.

  公开号：US11337449B2

  公开（公告）日：2022-05-24

  A synthetic nutritional composition comprising a vitamin for use to promote, support or optimise de novo myelination, in particular the de novo myelination trajectory, and/or brain structure, and/or brain connectivity, and/or intellectual potential and/or cognitive potential and/or learning potential and/or cognitive functioning in a subject, in particular a formula fed subject.

  一种包含维生素的合成营养组合物，用于促进、支持或优化受试者（尤其是配方喂养的受试者）的新生髓鞘化，特别是新生髓鞘化轨迹，和/或大脑结构，和/或大脑连通性，和/或智力潜能和/或认知潜能和/或学习潜能和/或认知功能。
• COMPOSITIONS AND THEIR USE
  申请人：NESTEC S.A.

  公开号：US20190254330A1

  公开（公告）日：2019-08-22

  A synthetic nutritional composition comprising a vitamin for use to promote, support or optimise de novo myelination, in particular the de novo myelination trajectory, and/or brain structure, and/or brain connectivity, and/or intellectual potential and/or cognitive potential and/or learning potential and/or cognitive functioning in a subject, in particular a formula fed subject.