N-[6-[4-(cyclohexylmethyl)triazol-1-yl]-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl]cyclohexanecarboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃类
• 英文名称: N-[6-[4-(cyclohexylmethyl)triazol-1-yl]-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl]cyclohexanecarboxamide
• 化学式: C₂₂H₃₄N₄O₃
• 分子量: 402.5
• InChiKey: KZFVAIZLKZENDH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  78.3
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS
  申请人：TACHDJIAN Catherine

  公开号：US20130295261A1

  公开（公告）日：2013-11-07

  The present invention provides isosorbide derivatives having the formula shown below and certain subgenera or species thereof, as flavor or taste modifiers, particularly, savory (“umami”) taste modifiers, savory flavoring agents and savory flavor enhancers in foods, beverages, and other comestible compositions,

  本发明提供以下式子及其特定亚属或种类的异山梨酯衍生物，作为味道或口感调节剂，特别是让食品、饮料和其他食品组合物具有鲜美（鲜味）口感的调节剂、风味剂和风味增强剂。
• US8420145B2
  申请人：——

  公开号：US8420145B2

  公开（公告）日：2013-04-16
• [EN] ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS<br/>[FR] DÉRIVÉS D'ISOSORBIDE ET LEUR UTILISATION EN TANT QUE MODIFICATEURS DE PARFUM, AGENTS DONNANT DU GOÛT ET EXHAUSTEURS DE GOÛT
  申请人：SENOMYX INC

  公开号：WO2009111447A2

  公开（公告）日：2009-09-11

  The present invention provides isosorbide derivatives having the formula shown below and certain subgenera or species thereof, as flavor or taste modifiers, particularly, savory ('umami') taste modifiers, savory flavoring agents and savory flavor enhancers in foods, beverages, and other comestible compositions,
• [EN] CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES<br/>[FR] THÉRAPIES BASÉES SUR UN LIGAND DE RÉCEPTEUR CHIMIOSENSORIEL
  申请人：ELCELYX THERAPEUTICS INC

  公开号：WO2012054526A2

  公开（公告）日：2012-04-26

  Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory receptor ligand. Also provided herein are chemosensory receptor ligand compositions and methods for the preparation thereof for use in the methods of the present invention.