Bis(4-methyl-1,3-dioxetan-2-yl)methanamine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧杂环丁烷
• 英文名称: Bis(4-methyl-1,3-dioxetan-2-yl)methanamine
• 英文别名: bis(4-methyl-1,3-dioxetan-2-yl)methanamine
• 化学式: C₇H₁₃NO₄
• 分子量: 175.18
• InChiKey: SYSSXVSXHJFERK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  62.9
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• SULFONIC ACID SALT COMPOUND OF 4-CARBAMOYL-5-HYDROXY-IMIDAZOLE DERIVATIVE
  申请人：Nobuo Kato

  公开号：US20100210855A1

  公开（公告）日：2010-08-19

  The object is to provide a stable SM-108 derivative, which is effective as a carcinostatic agent, particularly an SM-108 derivative having good storage stability. An SM-108 compound having good storage stability can be produced by producing an organic sulfonic acid salt compound of SM-108. Further, a crystalline SM-108 compound containing a trace amount of an organic carboxylic acid can be produced by using an aqueous solution of the organic sulfonic acid salt of SM-108, and by adding an alkali metal salt of an organic carboxylic acid to the aqueous solution to neutralize the aqueous solution and then causing the crystal precipitation in the solution.

  本发明旨在提供一种稳定的SM-108衍生物，其作为癌症静止剂具有良好的储存稳定性，特别是具有良好储存稳定性的SM-108衍生物。可以通过制备SM-108的有机磺酸盐化合物来生产具有良好储存稳定性的SM-108化合物。此外，可以使用SM-108的有机磺酸盐水溶液，并向水溶液中加入有机羧酸的碱金属盐以中和水溶液，然后在溶液中引起晶体沉淀，从而产生含有微量有机羧酸的晶体SM-108化合物。