1,19-diamino-4,8,12,16-tetraazanonadecane | 63833-74-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,19-diamino-4,8,12,16-tetraazanonadecane
• 英文别名: 4,8,12,16-Tetraazanonadecane-1,19-diamine；N'-[3-[3-[3-(3-aminopropylamino)propylamino]propylamino]propyl]propane-1,3-diamine
• CAS: 63833-74-9
• 化学式: C₁₅H₃₈N₆
• 分子量: 302.507
• InChiKey: UJMCAHHGTKIXAU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  21
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  100
• 氢给体数：
  6
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  1,19-diamino-4,8,12,16-tetraazanonadecane 、 二磷酸腺苷 生成 N'-[3-[3-[3-(3-aminopropylamino)propylamino]propylamino]propyl]propane-1,3-diamine;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate
  参考文献：
  名称：

  HOSSEINI, M. W.;LEHN, J. -M., NELV. CHIM. ACTA, 70,(1987) N 5, 1312-1319

  摘要：

  DOI：

文献信息

• LUBRICANT FOR A TWO CYCLE ENGINE
  申请人：Nippon Oil Co., Ltd.

  公开号：EP0636680A1

  公开（公告）日：1995-02-01

  A lubricant for a two cycle engine having as a basic oil a polyoxyalkylene glycol derivative expressed by general formula (1) which can realize, when used to lubricate bearing portions and sliding portions of the two cycle engine, remarkable reduction in generation of exhaust smoke, improvement in start-up capability, improvement in cleanability of preventing clogging of an exhaust system with carbon, improvement in cleanability inside the engine at high and low temperatures and improvement in withstand-load properties.

  一种用于双循环发动机的润滑油，其基础油为通式（1）表示的聚氧亚烷基二醇衍生物，当用于润滑双循环发动机的轴承部分和滑动部分时，可显著减少排气烟雾的产生，提高启动能力，提高防止排气系统积碳堵塞的清洁度，提高发动机内部在高温和低温下的清洁度，以及提高耐负荷性能。
• A method for producing aryl alkyl hydroperoxides
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0729938A2

  公开（公告）日：1996-09-04

  A method for producing aryl alkyl hydroperoxides which comprises selectively oxidizing an aryl alkyl hydrocarbon having the formula: wherein P and Q are hydrogen or an alkyl and may be the same or different from each other; x is an integer of 1-3; and Ar is an aromatic hydrocarbon group having a valence of x, with an oxygen-containing gas in the presence of a transition metal complex which contains, as a ligand, a cyclic polyfunctional amine compound having at least three nitrogen atoms in the ring forming molecular chain or an open chain polyfunctional amine compound having at least three nitrogen atoms in the main chain of the molecule.

  一种生产芳基烷基氢过氧化物的方法，包括选择性地氧化具有以下式子的芳基烷基碳氢化合物： 其中P和Q是氢或烷基，可以相同或不同；x是1-3的整数；Ar是化合价为x的芳香烃基团，在过渡金属配合物存在下，用含氧气体氧化，过渡金属配合物作为配体，含有在成环分子链中至少有三个氮原子的环状多官能胺化合物或在分子主链中至少有三个氮原子的开链多官能胺化合物。
• Processes and host cells for genome, pathway, and biomolecular engineering
  申请人：enEvolv, Inc.

  公开号：US10370654B2

  公开（公告）日：2019-08-06

  The present disclosure provides compositions and methods for genomic engineering.

  本公开提供了基因组工程的组合物和方法。
• Lfa-1 inhibitors and use thereof
  申请人：Soda Kuniyasu

  公开号：US20060281820A1

  公开（公告）日：2006-12-14

  The present invention provides an LFA-1 inhibitor comprising at least one member selected from the group consisting of polyamines represented by general formula (1) and pharmaceutical acceptable salts thereof: NH 2 —(CH 2 )m1-(NH)p1-(CH 2 )m2-(NH)p2-(CH 2 )m3-(NH)p3-(CH 2 )m4-(NH)p4-(CH 2 )m5-NH 2 (1), wherein at least two of m1 to m5 exceed 0, each of m1 to m5 is independently an integer of 0 to 7, the sum of m1+m2+m3+m4+m5 is 2 or more but less than 18, at least one of p1, p2, p3 and p4 is 1, and each of others independently represents 0 or 1. The present invention also provides a pharmaceutical composition containing the LFA-1 inhibitor and a method for the inhibition or the treatment of diseases.
• LFA-1 Inhibitors and Use Thereof
  申请人：Soda Kuniyasu

  公开号：US20100004342A1

  公开（公告）日：2010-01-07

  The present invention provides an LFA-1 inhibitor comprising at least one member selected from the group consisting of polyamines represented by general formula (I) and pharmaceutical acceptable salts thereof: NH 2 —(CH 2 )m1-(NH)p1-(CH 2 )m2-(NH)p2-(CH 2 )m3-(NH)p3-(CH 2 )m4-(NH)p4-(Cl 2 )m5-NH 2 (1), wherein at least two of m1 to m5 exceed 0, each of m1 to m5 is independently an integer of 0 to 7, the sum of m1+m2+m3+m4+m5 is 2 or more but less than 18, at least one of p1, p2, p3 and p4 is 1, and each of others independently represents 0 or 1. The present invention also provides a pharmaceutical composition containing the LFA-1 inhibitor and a method for the inhibition or the treatment of diseases.