4-(3-methoxypropyl)phenol | 74027-51-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-(3-methoxypropyl)phenol
• 英文别名: 4-methoxypropylphenol；p-(3-methoxypropyl)phenol
• CAS: 74027-51-3
• 化学式: C₁₀H₁₄O₂
• 分子量: 166.22
• InChiKey: UTCMCSUBKUIIOP-UHFFFAOYSA-N

物化性质

• 沸点：
  277.1±23.0 °C(Predicted)
• 密度：
  1.038±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  反式-4-丙基环己基甲酰氯 、 4-(3-methoxypropyl)phenol 生成
  参考文献：
  名称：

  Kitamura, Teruo; Mukoh, Akio; Era, Susumu, Molecular Crystals and Liquid Crystals (1969-1991), 1985, vol. 130, p. 231 - 248

  摘要：

  DOI：
• 作为产物：
  描述：

  (3-甲氧基丙基)苯 在 sodium hydroxide 、 甲酸 、 双氧水 作用下， 生成 4-(3-methoxypropyl)phenol
  参考文献：
  名称：

  Study of New Liquid Crystal Materials (II): Synthesis and Mesomorphic Properties of Alkoxymethylene Substituted Phenyl Cyclohexanecarboxylates

  摘要：

  DOI：

  10.1080/00268948408071842

文献信息

• Reactions of p-coumaryl alcohol model compounds with dimethyl carbonate. Towards the upgrading of lignin building blocks
  作者：Jessica N. G. Stanley、Maurizio Selva、Anthony F. Masters、Thomas Maschmeyer、Alvise Perosa

  DOI：10.1039/c3gc40334c

  日期：——

  Cinnamyl alcohol 1 and 4-(3-hydroxypropyl)phenol 2, two compounds resembling the lignin building block p-coumaryl alcohol, can be selectively transformed into different products by catalytic methodologies based on dimethyl carbonate (DMC) as a green solvent/reagent. Selectivity can be tuned as a function of the reaction temperature and of the nature of the catalyst. Basic catalysts such as K2CO3,

  肉桂醇1和4-（3-羟丙基）苯酚2这两种类似于木质素结构单元的对-香豆醇，可以通过基于碳酸二甲酯（DMC）作为绿色溶剂/试剂的催化方法选择性地转化为不同的产物。可以根据反应温度和催化剂的性质来调节选择性。碱性催化剂如K 2 CO 3，trioctylmethylphosphonium甲酯（[P 8881 ] [CH 3 OCOO]），和CsF /αAl 2 ö 3促进脂肪族羟基在90°C的选择性酯交换反应。但是，两性固体（如碱金属交换的八面沸石，NaX和NaY）在较高温度（165–180°C）下有选择地生成相应的烷基醚。的酚羟基2可以类似地用在高温下的八面沸石被甲基化。初步的选择性筛选说明了反应性趋势，并描述了可能升级木质素衍生化学构件的最有希望的合成途径中的一些。
• Silacyclohexane compounds, a liquid crystal composition comprising the
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：US05595686A1

  公开（公告）日：1997-01-21

  A silacyclohexane compound of the following formula (I) ##STR1## wherein R represents an organic residue; at least one of ##STR2## represents a substituted or unsubstituted trans-1-sila-1,4-cyclohexylene group or trans-4-sila-1,4-cyclohexylene group and the other represents a trans-1,4-cyclohexylene group, L.sub.1 and L.sub.2 independently represent H, F, Cl or CH.sub.3 ; X represents an organic residue or CN, F, Cl; and m and n are, respectively, 0 or 1 provided that m+n=1. Silacyclohexane compounds are useful in liquid crystal compositions and also in liquid crystal devices.

  以下是化学式为(I)的硅杂环己烷化合物： 其中，R代表有机残基；至少一个##STR2##表示取代或未取代的trans-1-硅-1,4-环己基基团或trans-4-硅-1,4-环己基基团，另一个表示trans-1,4-环己基，L1和L2独立地表示H，F，Cl或CH3；X表示有机残基或CN，F，Cl；m和n分别为0或1，前提是m+n=1。硅杂环己烷化合物可用于液晶组合物以及液晶装置中。
• Colorless liquid crystalline compounds
  申请人：Hitachi, Ltd.

  公开号：US04694098A1

  公开（公告）日：1987-09-15

  A colorless liquid crystalline compound having at least one 6-membered ring and non-cyclic end groups in the molecular skeleton, said 6-membered ring containing two or more carbon atoms, at least one of which is directly bonded to a methylene group of a non-cyclic group having an alkoxy group at another end has a wide mesomorphic range. When said colorless liquid crystalline compound is mixed with a liquid crystal composition, the resulting mixture also has an enlarged mesomorphic range and in almost all cases has a reduced viscosity.

  一种无色液晶化合物，其分子骨架中至少含有一个六元环和非环状末端基团，所述六元环含有两个或更多碳原子，其中至少一个直接与另一端具有烷氧基的非环状基团的亚甲基基团键合，具有广泛的介态范围。当该无色液晶化合物与液晶组分混合时，所得混合物也具有扩大的介态范围，并且在几乎所有情况下具有降低的粘度。
• PRODUCTION OF RENEWABLE FINE CHEMICALS AND LIQUID FUELS
  申请人：PURDUE RESEARCH FOUNDATION

  公开号：US20160272665A1

  公开（公告）日：2016-09-22

  Described herein is a process for conversion and upgrading of biomass to products. The process involves converting the biomass to primary lignin-derivatives and primary cellulose/hemicellulose derivatives, catalytically treating the primary lignin-derivatives to produce secondary lignin-derived products, and treating the primary cellulose/hemicellulose- derivatives to produce secondary cellulose/hemicellulose-derived products.

  本文描述了一种将生物质转化和升级为产品的过程。该过程涉及将生物质转化为初级木质素衍生物和初级纤维素/半纤维素衍生物，通过催化处理初级木质素衍生物来生产次生木质素衍生物产品，并处理初级纤维素/半纤维素衍生物以生产次生纤维素/半纤维素衍生物产品。
• Membrane stabilizing compounds having beta-receptor blocking activity, their preparation, method for treatment of arrhythmic conditions, and pharmaceutical preparations containing same
  申请人：Aktiebolaget Hässle

  公开号：EP0007294A2

  公开（公告）日：1980-01-23

  TThe present invention relates to new potent membrane stabilizing compounds of the formula wherein R1 is alkoxyalkyl. hydroxyalkyl or alkyl, which alkyl groups may be branched or straight, R2 is halogen or hyd- rogsn, R3 is hydrogen or alkyl, R4 and R5 are sams or different and are each hydrogen, sikoxy, alkyl, alkoxyalkyl, cyano, or hydroxy, n is 0, 1, 2, or 3. and X is -O-, -CHr. or . The present pounds are potent heart antiarrhythmic agents possessing membrane stabilizing effect and β-recsptor blocking effect in same clinical doses. The compounds are used In treating antiarrhythmic conditions. but can also be used in the trestment of hypertension. angina pectoris, or nervous heart The invention also relates to processes for preparing the compounds, method of treating anti- arrhythmic conditions and pharmaceutical preparations con- taining said compounds.

  本发明涉及新的强效膜稳定化合物，其式为 其中 R1 是烷氧基烷基、羟基烷基或烷基，其中烷基可以是支链或直链；R2 是卤素或水基；R3 是氢或烷基；R4 和 R5 是相同或不同的，并且各自是氢、烷氧基、烷基、烷氧基烷基、氰基或羟基；n 是 0、1、2 或 3；X 是 -O-、-CHr 或 。 本化合物是强效的心脏抗心律失常药物，在相同的临床剂量下，具有膜稳定作用和 β-抑制剂阻断作用。本发明还涉及制备本发明化合物的工艺、治疗抗心律失常的方法以及含有本发明化合物的药物制剂。